2149


Homo sapiens (NCBI)

Features
Gene ID: 2149
  
Biological name :
  
Synonyms : CF2R|HTR|PAR-1|PAR1|TR / coagulation factor II thrombin receptor / F2R
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1569642_at (Human Genome U133 Plus 2.0 Array)   203989_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 166362740
RefSeq - 913402869
RefSeq - NC_000005.10
RefSeq - NG_032906.1
RefSeq - NP_001298242.1
RefSeq - NP_001983.2
RefSeq - NM_001311313.1
RefSeq - NM_001992.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000181104 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity ISS
 biological_processGO:0002248 connective tissue replacement involved in inflammatory response wound healing IDA
 biological_processGO:0003105 negative regulation of glomerular filtration ISS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0006954 inflammatory response ISS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISS
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway ISS
 biological_processGO:0007529 establishment of synaptic specificity at neuromuscular junction ISS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009611 response to wounding IDA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISS
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030193 regulation of blood coagulation IDA
 biological_processGO:0030194 positive regulation of blood coagulation IDA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0032496 response to lipopolysaccharide ISS
 biological_processGO:0032651 regulation of interleukin-1 beta production ISS
 biological_processGO:0032967 positive regulation of collagen biosynthetic process IDA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction ISS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEP
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0043547 positive regulation of GTPase activity IMP
 biological_processGO:0045217 cell-cell junction maintenance IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045907 positive regulation of vasoconstriction ISS
 biological_processGO:0045987 positive regulation of smooth muscle contraction ISS
 biological_processGO:0046427 positive regulation of JAK-STAT cascade NAS
 biological_processGO:0048873 homeostasis of number of cells within a tissue ISS
 biological_processGO:0051209 release of sequestered calcium ion into cytosol ISS
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ISS
 biological_processGO:0051928 positive regulation of calcium ion transport ISS
 biological_processGO:0051930 regulation of sensory perception of pain ISS
 biological_processGO:0060155 platelet dense granule organization IC
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0070493 thrombin-activated receptor signaling pathway IEA
 biological_processGO:0099553 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission IEA
 biological_processGO:1900134 negative regulation of renin secretion into blood stream ISS
 biological_processGO:2000484 positive regulation of interleukin-8 secretion IDA
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005901 caveola IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0031094 platelet dense tubular network IDA
 cellular_componentGO:0031594 neuromuscular junction ISS
 cellular_componentGO:0045211 postsynaptic membrane ISS
 molecular_functionGO:0001965 G-protein alpha-subunit binding ISS
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015057 thrombin-activated receptor activity IDA
 molecular_functionGO:0031681 G-protein beta-subunit binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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