21687


Mus musculus (NCBI)

Features
Gene ID: 21687
  
Biological name :
  
Synonyms : AA517024|Cd202b|Hyk|STK1|Tie-2|Tie2 / Tek / TEK receptor tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418788_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 111185951
RefSeq - 568928760
RefSeq - 594542448
RefSeq - 594542525
RefSeq - NC_000070.6
RefSeq - NP_001277478.1
RefSeq - NP_001277480.1
RefSeq - NP_038718.2
RefSeq - XP_006502993.1
RefSeq - NM_001290549.1
RefSeq - NM_001290551.1
RefSeq - NM_013690.3
RefSeq - XM_006502930.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000006386 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis TAS
 biological_processGO:0001569 branching involved in blood vessel morphogenesis TAS
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001935 endothelial cell proliferation IMP
 biological_processGO:0001936 regulation of endothelial cell proliferation TAS
 biological_processGO:0002040 sprouting angiogenesis ISO
 biological_processGO:0002741 positive regulation of cytokine secretion involved in immune response IDA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007160 cell-matrix adhesion IMP
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ISO
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010595 positive regulation of endothelial cell migration TAS
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016525 negative regulation of angiogenesis ISO
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030334 regulation of cell migration IMP
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0032526 response to retinoic acid IDA
 biological_processGO:0032878 regulation of establishment or maintenance of cell polarity ISO
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IGI
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading ISO
 biological_processGO:0042307 positive regulation of protein import into nucleus IDA
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISO
 biological_processGO:0043627 response to estrogen ISO
 biological_processGO:0045765 regulation of angiogenesis IMP
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045785 positive regulation of cell adhesion IMP
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048014 Tie signaling pathway TAS
 biological_processGO:0051259 protein complex oligomerization ISO
 biological_processGO:0051894 positive regulation of focal adhesion assembly ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling ISO
 biological_processGO:0060347 heart trabecula formation IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0072012 glomerulus vasculature development ISO
 biological_processGO:0098609 cell-cell adhesion IMP
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling IGI
 biological_processGO:1902533 positive regulation of intracellular signal transduction ISO
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization ISO
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IMP
 cellular_componentGO:0001725 stress fiber ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005902 microvillus ISO
 cellular_componentGO:0005911 cell-cell junction ISO
 cellular_componentGO:0009925 basal plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISM
 cellular_componentGO:0016323 basolateral plasma membrane ISO
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038023 signaling receptor activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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