21752


Mus musculus (NCBI)

Features
Gene ID: 21752
  
Biological name :
  
Synonyms : EST2|TCS1|TP2|TR|TRT / telomerase reverse transcriptase / Tert
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1450254_at (Mouse Genome 430 2.0 Array)   1456941_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1377037964
RefSeq - 1377038043
RefSeq - 568983274
RefSeq - 568983278
RefSeq - 568983280
RefSeq - 568983282
RefSeq - 6678291
RefSeq - NC_000079.6
RefSeq - NP_001349316.1
RefSeq - NP_001349317.1
RefSeq - NP_033380.1
RefSeq - XP_006517274.1
RefSeq - XP_006517275.1
RefSeq - XP_006517276.1
RefSeq - XP_006517277.1
RefSeq - XM_006517212.3
RefSeq - XM_006517213.3
RefSeq - XM_006517214.3
RefSeq - NM_001362387.1
RefSeq - NM_001362388.1
RefSeq - NM_009354.2
RefSeq - XR_382432.3
RefSeq - XR_001780771.1
RefSeq - XR_001780772.1
RefSeq - XM_006517211.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000021611 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001172 transcription, RNA-templated ISO
 biological_processGO:0006278 RNA-dependent DNA biosynthetic process ISO
 biological_processGO:0007004 telomere maintenance via telomerase TAS
 biological_processGO:0007005 mitochondrion organization ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0022616 DNA strand elongation ISO
 biological_processGO:0030177 positive regulation of Wnt signaling pathway ISO
 biological_processGO:0030422 production of siRNA involved in RNA interference ISO
 biological_processGO:0031647 regulation of protein stability ISO
 biological_processGO:0032092 positive regulation of protein binding ISO
 biological_processGO:0032774 RNA biosynthetic process ISO
 biological_processGO:0042635 positive regulation of hair cycle IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0046326 positive regulation of glucose import IMP
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity ISO
 biological_processGO:0060253 negative regulation of glial cell proliferation ISO
 biological_processGO:0070200 establishment of protein localization to telomere ISO
 biological_processGO:0071456 cellular response to hypoxia ISO
 biological_processGO:0071897 DNA biosynthetic process ISO
 biological_processGO:0090399 replicative senescence ISO
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle ISO
 biological_processGO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II ISO
 biological_processGO:1903620 positive regulation of transdifferentiation ISO
 biological_processGO:1903704 negative regulation of production of siRNA involved in RNA interference ISO
 biological_processGO:1904173 regulation of histone demethylase activity (H3-K4 specific) TAS
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation ISO
 biological_processGO:1904751 positive regulation of protein localization to nucleolus ISO
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration ISO
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process ISO
 biological_processGO:2000648 positive regulation of stem cell proliferation IMP
 biological_processGO:2000773 negative regulation of cellular senescence ISO
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
 cellular_componentGO:0000333 telomerase catalytic core complex ISO
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005697 telomerase holoenzyme complex ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016605 PML body ISO
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0031379 RNA-directed RNA polymerase complex ISO
 cellular_componentGO:0042645 mitochondrial nucleoid ISO
 cellular_componentGO:1990572 TERT-RMRP complex ISO
 molecular_functionGO:0000049 tRNA binding ISO
 molecular_functionGO:0001223 transcription coactivator binding ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003720 telomerase activity TAS
 molecular_functionGO:0003721 telomerase RNA reverse transcriptase activity ISO
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0003964 RNA-directed DNA polymerase activity ISO
 molecular_functionGO:0003968 RNA-directed 5"-3" RNA polymerase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity ISO
 molecular_functionGO:0042162 telomeric DNA binding IBA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047485 protein N-terminus binding ISO
 molecular_functionGO:0051087 chaperone binding ISO
 molecular_functionGO:0070034 telomerase RNA binding ISO
 molecular_functionGO:0098680 template-free RNA nucleotidyltransferase ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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