21813


Mus musculus (NCBI)

Features
Gene ID: 21813
  
Biological name :
  
Synonyms : 1110020H15Rik|AU042018|DNIIR|RIIDN|TBR-II|TbetaR-II|TbetaRII / Tgfbr2 / transforming growth factor, beta receptor II
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422019_at (Mouse Genome 430 2.0 Array)   1425444_a_at (Mouse Genome 430 2.0 Array)   1426397_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_033397.3
RefSeq - NP_083851.3
RefSeq - NC_000075.6
RefSeq - 239787881
RefSeq - 239787884
RefSeq - NM_009371.3
RefSeq - NM_029575.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000032440 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IMP
 biological_processGO:0002088 lens development in camera-type eye IMP
 biological_processGO:0002651 positive regulation of tolerance induction to self antigen IMP
 biological_processGO:0002663 positive regulation of B cell tolerance induction IMP
 biological_processGO:0002666 positive regulation of T cell tolerance induction IMP
 biological_processGO:0003148 outflow tract septum morphogenesis IMP
 biological_processGO:0003149 membranous septum morphogenesis IMP
 biological_processGO:0003151 outflow tract morphogenesis IMP
 biological_processGO:0003181 atrioventricular valve morphogenesis IMP
 biological_processGO:0003186 tricuspid valve morphogenesis IMP
 biological_processGO:0003214 cardiac left ventricle morphogenesis IMP
 biological_processGO:0003274 endocardial cushion fusion IMP
 biological_processGO:0003417 growth plate cartilage development IGI
 biological_processGO:0003430 growth plate cartilage chondrocyte growth IMP
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006898 receptor-mediated endocytosis ISO
 biological_processGO:0006915 apoptotic process ISO
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0007182 common-partner SMAD protein phosphorylation ISO
 biological_processGO:0007219 Notch signaling pathway IDA
 biological_processGO:0007224 smoothened signaling pathway IMP
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0007389 pattern specification process IBA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009887 animal organ morphogenesis ISO
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010634 positive regulation of epithelial cell migration IMP
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation ISO
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISO
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030324 lung development IMP
 biological_processGO:0032147 activation of protein kinase activity IDA
 biological_processGO:0032924 activin receptor signaling pathway IBA
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0042493 response to drug ISO
 biological_processGO:0043011 myeloid dendritic cell differentiation IMP
 biological_processGO:0045766 positive regulation of angiogenesis IGI
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0051138 positive regulation of NK T cell differentiation IMP
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0060044 negative regulation of cardiac muscle cell proliferation ISO
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0060412 ventricular septum morphogenesis IMP
 biological_processGO:0060425 lung morphogenesis IMP
 biological_processGO:0060433 bronchus development IMP
 biological_processGO:0060434 bronchus morphogenesis IMP
 biological_processGO:0060439 trachea morphogenesis IMP
 biological_processGO:0060440 trachea formation IMP
 biological_processGO:0060443 mammary gland morphogenesis IMP
 biological_processGO:0060463 lung lobe morphogenesis IMP
 biological_processGO:0062009 secondary palate development IMP
 biological_processGO:0070723 response to cholesterol ISO
 biological_processGO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation IMP
 biological_processGO:1905315 cell proliferation involved in endocardial cushion morphogenesis IMP
 biological_processGO:1905316 superior endocardial cushion morphogenesis IMP
 biological_processGO:1905317 inferior endocardial cushion morphogenesis IMP
 biological_processGO:1990086 lens fiber cell apoptotic process IDA
 biological_processGO:1990428 miRNA transport IMP
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process ISO
 biological_processGO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0048179 activin receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004675 transmembrane receptor protein serine/threonine kinase activity ISO
 molecular_functionGO:0005024 transforming growth factor beta-activated receptor activity ISO
 molecular_functionGO:0005026 transforming growth factor beta receptor activity, type II ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding ISO
 molecular_functionGO:0034713 type I transforming growth factor beta receptor binding ISO
 molecular_functionGO:0034714 type III transforming growth factor beta receptor binding ISO
 molecular_functionGO:0038023 signaling receptor activity IEA
 molecular_functionGO:0046332 SMAD binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048185 activin binding IBA
 molecular_functionGO:0050431 transforming growth factor beta binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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