2185


Homo sapiens (NCBI)

Features
Gene ID: 2185
  
Biological name :
  
Synonyms : CADTK|CAKB|FADK2|FAK2|PKB|PTK|PYK2|RAFTK / protein tyrosine kinase 2 beta / PTK2B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203110_at (Human Genome U133 Plus 2.0 Array)   203111_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016868705.1
RefSeq - 1034659624
RefSeq - 1034659626
RefSeq - 27886584
RefSeq - 27886586
RefSeq - 27886588
RefSeq - 27886590
RefSeq - 530387660
RefSeq - 530387662
RefSeq - 767950661
RefSeq - 767950664
RefSeq - NC_000008.11
RefSeq - NG_029510.1
RefSeq - NP_004094.3
RefSeq - NP_775266.1
RefSeq - NP_775267.1
RefSeq - NP_775268.1
RefSeq - XP_005273504.1
RefSeq - XP_005273505.1
RefSeq - XP_011542743.1
RefSeq - XP_011542744.1
RefSeq - XP_016868703.1
RefSeq - XP_016868704.1
RefSeq - 1034659618
RefSeq - NM_004103.4
RefSeq - NM_173174.2
RefSeq - NM_173175.2
RefSeq - NM_173176.2
RefSeq - XM_011544442.3
RefSeq - XM_017013214.1
RefSeq - XM_017013215.1
RefSeq - XM_017013216.2
RefSeq - XM_005273447.4
RefSeq - XM_005273448.5
RefSeq - XM_011544441.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000120899 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0001525 angiogenesis IBA
 biological_processGO:0001556 oocyte maturation IEA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IMP
 biological_processGO:0002040 sprouting angiogenesis ISS
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002315 marginal zone B cell differentiation ISS
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006968 cellular defense response ISS
 biological_processGO:0006970 response to osmotic stress IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway IMP
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007172 signal complex assembly IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IMP
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0009725 response to hormone IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0010226 response to lithium ion IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IDA
 biological_processGO:0010656 negative regulation of muscle cell apoptotic process IEA
 biological_processGO:0010752 regulation of cGMP-mediated signaling IEA
 biological_processGO:0010758 regulation of macrophage chemotaxis ISS
 biological_processGO:0010976 positive regulation of neuron projection development IMP
 biological_processGO:0014009 glial cell proliferation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030155 regulation of cell adhesion IMP
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0030502 negative regulation of bone mineralization ISS
 biological_processGO:0030838 positive regulation of actin filament polymerization IMP
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032960 regulation of inositol trisphosphate biosynthetic process ISS
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway ISS
 biological_processGO:0035902 response to immobilization stress IEA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation ISS
 biological_processGO:0038110 interleukin-2-mediated signaling pathway TAS
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0042976 activation of Janus kinase activity IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043149 stress fiber assembly IEA
 biological_processGO:0043267 negative regulation of potassium ion transport IDA
 biological_processGO:0043507 positive regulation of JUN kinase activity IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0043534 blood vessel endothelial cell migration IEA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISS
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0045453 bone resorption ISS
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045638 negative regulation of myeloid cell differentiation IMP
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IMP
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0046777 protein autophosphorylation TAS
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048041 focal adhesion assembly IEA
 biological_processGO:0048167 regulation of synaptic plasticity TAS
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050848 regulation of calcium-mediated signaling IEA
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity IEA
 biological_processGO:0051279 regulation of release of sequestered calcium ion into cytosol ISS
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0051968 positive regulation of synaptic transmission, glutamatergic ISS
 biological_processGO:0060291 long-term synaptic potentiation ISS
 biological_processGO:0060292 long term synaptic depression IEA
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0070098 chemokine-mediated signaling pathway ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071300 cellular response to retinoic acid IMP
 biological_processGO:0071498 cellular response to fluid shear stress IEA
 biological_processGO:0090630 activation of GTPase activity IEA
 biological_processGO:2000058 regulation of ubiquitin-dependent protein catabolic process IDA
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IEA
 biological_processGO:2000114 regulation of establishment of cell polarity ISS
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization ISS
 biological_processGO:2000310 regulation of NMDA receptor activity ISS
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential ISS
 biological_processGO:2000538 positive regulation of B cell chemotaxis ISS
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0014069 postsynaptic density TAS
 cellular_componentGO:0017146 NMDA selective glutamate receptor complex ISS
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0044297 cell body ISS
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0097440 apical dendrite ISS
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity ISS
 molecular_functionGO:0004713 protein tyrosine kinase activity IDA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IDA
 molecular_functionGO:0004972 NMDA glutamate receptor activity ISS
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IMP
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0043423 3-phosphoinositide-dependent protein kinase binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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