22030


Mus musculus (NCBI)

Features
Gene ID: 22030
  
Biological name :
  
Synonyms : AI325259 / TNF receptor-associated factor 2 / Traf2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1451233_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568913284
RefSeq - 568913286
RefSeq - 594150400
RefSeq - 83921633
RefSeq - NC_000068.7
RefSeq - NP_001277342.1
RefSeq - NP_033448.2
RefSeq - XP_006497912.1
RefSeq - XP_006497913.1
RefSeq - NM_001290413.1
RefSeq - NM_009422.3
RefSeq - XM_006497849.1
RefSeq - XM_006497850.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000026942 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002726 positive regulation of T cell cytokine production ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity ISO
 biological_processGO:0030163 protein catabolic process IMP
 biological_processGO:0032743 positive regulation of interleukin-2 production ISO
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway ISO
 biological_processGO:0034351 negative regulation of glial cell apoptotic process ISO
 biological_processGO:0034622 cellular protein-containing complex assembly IDA
 biological_processGO:0042981 regulation of apoptotic process ISO
 biological_processGO:0043066 negative regulation of apoptotic process NAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043507 positive regulation of JUN kinase activity ISO
 biological_processGO:0046328 regulation of JNK cascade IDA
 biological_processGO:0051023 regulation of immunoglobulin secretion IMP
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0051291 protein heterooligomerization ISO
 biological_processGO:0051865 protein autoubiquitination ISO
 biological_processGO:0070207 protein homotrimerization ISO
 biological_processGO:0070534 protein K63-linked ubiquitination ISO
 biological_processGO:0071732 cellular response to nitric oxide IMP
 biological_processGO:0090073 positive regulation of protein homodimerization activity ISO
 biological_processGO:0097300 programmed necrotic cell death IMP
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway IDA
 biological_processGO:1903721 positive regulation of I-kappaB phosphorylation IDA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway ISO
 cellular_componentGO:0000151 ubiquitin ligase complex ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005938 cell cortex ISO
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0012506 vesicle membrane IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0035631 CD40 receptor complex IDA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0097057 TRAF2-GSTP1 complex ISO
 cellular_componentGO:1990597 AIP1-IRE1 complex IPI
 cellular_componentGO:1990604 IRE1-TRAF2-ASK1 complex ISO
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005164 tumor necrosis factor receptor binding ISO
 molecular_functionGO:0005174 CD40 receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0031996 thioesterase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046625 sphingolipid binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr