22339


Mus musculus (NCBI)

Features
Gene ID: 22339
  
Biological name :
  
Synonyms : vascular endothelial growth factor A / Vegfa / Vegf|Vpf
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1420909_at (Mouse Genome 430 2.0 Array)   1451959_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 160358799
RefSeq - 160358803
RefSeq - 160358807
RefSeq - 160358811
RefSeq - 160358815
RefSeq - 160358817
RefSeq - 559767228
RefSeq - 559767230
RefSeq - 559767232
RefSeq - 949928101
RefSeq - NC_000083.6
RefSeq - NP_001020421.2
RefSeq - NP_001020428.2
RefSeq - NP_001103736.1
RefSeq - NP_001103737.1
RefSeq - NP_001103738.1
RefSeq - NP_001273985.1
RefSeq - NP_001273986.1
RefSeq - NP_001273987.1
RefSeq - NP_001303970.1
RefSeq - NP_033531.3
RefSeq - NM_001025250.3
RefSeq - NM_001025257.3
RefSeq - NM_001110266.1
RefSeq - NM_001110267.1
RefSeq - NM_001110268.1
RefSeq - NM_001287056.1
RefSeq - NM_001287057.1
RefSeq - NM_001287058.1
RefSeq - NM_001317041.1
RefSeq - NM_009505.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000023951 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0001525 angiogenesis ISO
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001938 positive regulation of endothelial cell proliferation ISO
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0001946 lymphangiogenesis IGI
 biological_processGO:0001974 blood vessel remodeling ISO
 biological_processGO:0002040 sprouting angiogenesis IDA
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis ISO
 biological_processGO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis IMP
 biological_processGO:0002052 positive regulation of neuroblast proliferation IGI
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IDA
 biological_processGO:0002092 positive regulation of receptor internalization ISO
 biological_processGO:0002575 basophil chemotaxis ISO
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0003151 outflow tract morphogenesis IMP
 biological_processGO:0003169 coronary vein morphogenesis IMP
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development ISO
 biological_processGO:0007498 mesoderm development IMP
 biological_processGO:0007595 lactation IMP
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008360 regulation of cell shape ISO
 biological_processGO:0009967 positive regulation of signal transduction ISO
 biological_processGO:0010595 positive regulation of endothelial cell migration ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010719 negative regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0010749 regulation of nitric oxide mediated signal transduction ISO
 biological_processGO:0016477 cell migration IGI
 biological_processGO:0022408 negative regulation of cell-cell adhesion IGI
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030224 monocyte differentiation ISO
 biological_processGO:0030225 macrophage differentiation ISO
 biological_processGO:0030324 lung development IMP
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030855 epithelial cell differentiation IMP
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway ISO
 biological_processGO:0031077 post-embryonic camera-type eye development IMP
 biological_processGO:0031334 positive regulation of protein complex assembly ISO
 biological_processGO:0031954 positive regulation of protein autophosphorylation ISO
 biological_processGO:0032147 activation of protein kinase activity ISO
 biological_processGO:0032793 positive regulation of CREB transcription factor activity ISO
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation ISO
 biological_processGO:0035148 tube formation ISO
 biological_processGO:0035767 endothelial cell chemotaxis ISO
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus ISO
 biological_processGO:0036303 lymph vessel morphogenesis IMP
 biological_processGO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway ISO
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway ISO
 biological_processGO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway ISO
 biological_processGO:0038190 VEGF-activated neuropilin signaling pathway ISO
 biological_processGO:0040008 regulation of growth IMP
 biological_processGO:0042088 T-helper 1 type immune response ISO
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043069 negative regulation of programmed cell death ISO
 biological_processGO:0043117 positive regulation of vascular permeability ISO
 biological_processGO:0043129 surfactant homeostasis IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0043406 positive regulation of MAP kinase activity ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043542 endothelial cell migration IMP
 biological_processGO:0045599 negative regulation of fat cell differentiation IMP
 biological_processGO:0045601 regulation of endothelial cell differentiation IDA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IMP
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045779 negative regulation of bone resorption ISO
 biological_processGO:0045785 positive regulation of cell adhesion ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway ISO
 biological_processGO:0048255 mRNA stabilization ISO
 biological_processGO:0048286 lung alveolus development ISO
 biological_processGO:0048469 cell maturation IMP
 biological_processGO:0048514 blood vessel morphogenesis IMP
 biological_processGO:0048593 camera-type eye morphogenesis IMP
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0048739 cardiac muscle fiber development IMP
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IDA
 biological_processGO:0048842 positive regulation of axon extension involved in axon guidance IMP
 biological_processGO:0048844 artery morphogenesis IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IMP
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0050918 positive chemotaxis ISO
 biological_processGO:0050927 positive regulation of positive chemotaxis ISO
 biological_processGO:0050930 induction of positive chemotaxis ISO
 biological_processGO:0051272 positive regulation of cellular component movement ISO
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0060319 primitive erythrocyte differentiation IMP
 biological_processGO:0060326 cell chemotaxis ISO
 biological_processGO:0060346 bone trabecula formation IMP
 biological_processGO:0060426 lung vasculature development IMP
 biological_processGO:0060749 mammary gland alveolus development IMP
 biological_processGO:0060754 positive regulation of mast cell chemotaxis ISO
 biological_processGO:0060948 cardiac vascular smooth muscle cell development IMP
 biological_processGO:0060978 angiogenesis involved in coronary vascular morphogenesis ISO
 biological_processGO:0060982 coronary artery morphogenesis IMP
 biological_processGO:0061304 retinal blood vessel morphogenesis IMP
 biological_processGO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia ISO
 biological_processGO:0061430 bone trabecula morphogenesis IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071456 cellular response to hypoxia ISO
 biological_processGO:0071542 dopaminergic neuron differentiation IGI
 biological_processGO:0071679 commissural neuron axon guidance IMP
 biological_processGO:0090037 positive regulation of protein kinase C signaling ISO
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis ISO
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IDA
 biological_processGO:0090259 regulation of retinal ganglion cell axon guidance IMP
 biological_processGO:0097475 motor neuron migration IMP
 biological_processGO:0097533 cellular stress response to acid chemical ISO
 biological_processGO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation ISO
 biological_processGO:1900745 positive regulation of p38MAPK cascade ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1901492 positive regulation of lymphangiogenesis IDA
 biological_processGO:1901532 regulation of hematopoietic progenitor cell differentiation IDA
 biological_processGO:1901727 positive regulation of histone deacetylase activity ISO
 biological_processGO:1902336 positive regulation of retinal ganglion cell axon guidance IMP
 biological_processGO:1902966 positive regulation of protein localization to early endosome ISO
 biological_processGO:1903572 positive regulation of protein kinase D signaling ISO
 biological_processGO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISO
 biological_processGO:1903672 positive regulation of sprouting angiogenesis ISO
 biological_processGO:2000573 positive regulation of DNA biosynthetic process ISO
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005604 basement membrane ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030141 secretory granule ISO
 cellular_componentGO:0031982 vesicle ISO
 molecular_functionGO:0001968 fibronectin binding ISO
 molecular_functionGO:0005102 signaling receptor binding IDA
 molecular_functionGO:0005125 cytokine activity ISO
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding ISO
 molecular_functionGO:0005172 vascular endothelial growth factor receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity ISO
 molecular_functionGO:0008201 heparin binding ISO
 molecular_functionGO:0019838 growth factor binding ISO
 molecular_functionGO:0038191 neuropilin binding ISO
 molecular_functionGO:0042056 chemoattractant activity ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043183 vascular endothelial growth factor receptor 1 binding ISO
 molecular_functionGO:0043184 vascular endothelial growth factor receptor 2 binding ISO
 molecular_functionGO:0043185 vascular endothelial growth factor receptor 3 binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0048018 receptor ligand activity ISO
 molecular_functionGO:0050840 extracellular matrix binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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