2247


Homo sapiens (NCBI)

Features
Gene ID: 2247
  
Biological name :
  
Synonyms : BFGF|FGF-2|FGFB|HBGF-2 / FGF2 / fibroblast growth factor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204421_s_at (Human Genome U133 Plus 2.0 Array)   204422_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1371565425
RefSeq - 153285461
RefSeq - NC_000004.12
RefSeq - NG_029067.2
RefSeq - NP_001348594.1
RefSeq - NP_001997.5
RefSeq - NM_001361665.1
RefSeq - NM_002006.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000138685 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IDA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis IGI
 biological_processGO:0006661 phosphatidylinositol biosynthetic process IDA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007265 Ras protein signal transduction TAS
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0008284 positive regulation of cell proliferation IGI
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010764 negative regulation of fibroblast migration IDA
 biological_processGO:0010863 positive regulation of phospholipase C activity IDA
 biological_processGO:0014843 growth factor dependent regulation of skeletal muscle satellite cell proliferation IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030214 hyaluronan catabolic process IDA
 biological_processGO:0032958 inositol phosphate biosynthetic process IDA
 biological_processGO:0035019 somatic stem cell population maintenance TAS
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0038001 paracrine signaling ISS
 biological_processGO:0042060 wound healing TAS
 biological_processGO:0042660 positive regulation of cell fate specification IDA
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IGI
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration IDA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IDA
 biological_processGO:0045765 regulation of angiogenesis TAS
 biological_processGO:0045766 positive regulation of angiogenesis IGI
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048598 embryonic morphogenesis TAS
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IDA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060045 positive regulation of cardiac muscle cell proliferation IDA
 biological_processGO:0060548 negative regulation of cell death IDA
 biological_processGO:0060591 chondroblast differentiation IDA
 biological_processGO:0061045 negative regulation of wound healing IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0072089 stem cell proliferation NAS
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IDA
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IMP
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IGI
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation IGI
 biological_processGO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor IDA
 biological_processGO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor IDA
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IGI
 biological_processGO:2001028 positive regulation of endothelial cell chemotaxis IGI
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IPI
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005178 integrin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IDA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IDA
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0090722 receptor-receptor interaction IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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