2252


Homo sapiens (NCBI)
regulationcellactivityproliferationgrowthfactorsignalingmorphogenesisproteininvolvedreceptorphosphorylationepitheliallungbindingfibroblastkeratinocytepeptidyl-tyrosinephosphatidylinositol-kinasebranchingsalivarygland-kinasemapkcascadesignaltransductionpathwayepidermis

Features
Gene ID: 2252
  
Biological name :
  
Synonyms : FGF7 / fibroblast growth factor 7 / HBGF-7|KGF
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554741_s_at (Human Genome U133 Plus 2.0 Array)   1555102_at (Human Genome U133 Plus 2.0 Array)   1555103_s_at (Human Genome U133 Plus 2.0 Array)   205782_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4503705
RefSeq - NC_000015.10
RefSeq - NG_029159.1
RefSeq - NP_002000.1
RefSeq - NM_002009.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000140285 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to endogenous stimulusresponse to chemicalanatomical structure developmentresponse to stressmesenchymal cell proliferationregulation of molecular functionepithelial cell proliferationmolting cyclecellular component organizationactin filament-based processmacromolecule localizationcellular localizationbiosynthetic processresponse to external stimuluslocalization of cellmovement of cell or subcellular componenttissue migrationcell divisionestablishment of localizationdevelopmental growthnitronitrogen compound metabolic processcell cell communicationcellucellular metabolic processprimaprimary metabolic processorganorganic substance metabolic processcellucellular response to stimulusresporesponse to endogenous stimulusresporesponse to chemicalanatoanatomical structure developmentresporesponse to stressmesenmesenchymal cell proliferationregulregulation of molecular functionepithepithelial cell proliferationmoltimolting cyclecellucellular component organizationactinactin filament-based processmacromacromolecule localizationcellucellular localizationbiosybiosynthetic processresporesponse to external stimuluslocallocalization of cellmovemmovement of cell or subcellular componenttissutissue migrationcell cell divisionestabestablishment of localizationdeveldevelopmental growth
catalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, acting on a proteintransferase activityprotein bindingreceptor regulator activityion bindingcarbohydrate derivative bindingsulfur compound bindingcatalytic activity, catalytic activity, acting on a proteintransferase activitytransferase activityprotein bindingprotein bindingreceptor regulator areceptor regulator activityion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingsulfur compound bindsulfur compound binding
extracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regioncellorganelleextracellular regionextracellular regioncellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0008284 positive regulation of cell proliferation IGI
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0009611 response to wounding TAS
 biological_processGO:0010463 mesenchymal cell proliferation IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010838 positive regulation of keratinocyte proliferation IDA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0031069 hair follicle morphogenesis IEA
 biological_processGO:0031532 actin cytoskeleton reorganization IDA
 biological_processGO:0034394 protein localization to cell surface IDA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050918 positive chemotaxis IDA
 biological_processGO:0051549 positive regulation of keratinocyte migration IDA
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060445 branching involved in salivary gland morphogenesis IEA
 biological_processGO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis IDA
 biological_processGO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling IEA
 biological_processGO:0061033 secretion by lung epithelial cell involved in lung growth IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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