2260


Homo sapiens (NCBI)

Features
Gene ID: 2260
  
Biological name :
  
Synonyms : BFGFR|CD331|CEK|ECCL|FGFBR|FGFR-1|FLG|FLT-2|FLT2|HBGFR|HH2|HRTFDS|KAL2|N-SAM|OGD|bFGF-R-1 / FGFR1 / fibroblast growth factor receptor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207822_at (Human Genome U133 Plus 2.0 Array)   207937_x_at (Human Genome U133 Plus 2.0 Array)   210973_s_at (Human Genome U133 Plus 2.0 Array)   211535_s_at (Human Genome U133 Plus 2.0 Array)   215404_x_at (Human Genome U133 Plus 2.0 Array)   222164_at (Human Genome U133 Plus 2.0 Array)   226705_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 578815249
RefSeq - 578815253
RefSeq - 767950666
RefSeq - 767950668
RefSeq - 767950670
RefSeq - 767950672
RefSeq - 767950674
RefSeq - 767950680
RefSeq - 767950682
RefSeq - 767950684
RefSeq - 767950688
RefSeq - 767950690
RefSeq - NC_000008.11
RefSeq - NG_007729.1
RefSeq - 1034659644
RefSeq - 1034659646
RefSeq - 1034659648
RefSeq - 1034659653
RefSeq - XP_006716366.1
RefSeq - XP_006716367.1
RefSeq - XP_006716370.1
RefSeq - XP_006716373.1
RefSeq - XP_006716374.1
RefSeq - XP_006716375.1
RefSeq - XP_006716377.1
RefSeq - XP_011542745.1
RefSeq - XP_011542746.1
RefSeq - XP_011542747.1
RefSeq - XP_011542748.1
RefSeq - XP_011542749.1
RefSeq - XP_011542750.1
RefSeq - XP_011542751.1
RefSeq - XP_011542752.1
RefSeq - XP_011542753.1
RefSeq - XP_011542754.1
RefSeq - XP_016868708.1
RefSeq - XP_016868709.1
RefSeq - XP_016868710.1
RefSeq - XP_016868711.1
RefSeq - XP_016868713.1
RefSeq - XP_016868714.1
RefSeq - XP_016868715.1
RefSeq - XP_016868716.1
RefSeq - XP_016868718.1
RefSeq - XP_016868719.1
RefSeq - XP_016868720.1
RefSeq - XP_024302865.1
RefSeq - 1034659655
RefSeq - 1034659640
RefSeq - 1034659658
RefSeq - 1034659660
RefSeq - 1034659666
RefSeq - 1034659668
RefSeq - 1034659670
RefSeq - 105990522
RefSeq - 1229732560
RefSeq - 1229732571
RefSeq - 1237937818
RefSeq - 1237938292
RefSeq - 13186234
RefSeq - 13186236
RefSeq - 13186251
RefSeq - NP_001167534.1
RefSeq - NP_001167535.1
RefSeq - NP_001167536.1
RefSeq - NP_001167537.1
RefSeq - NP_001167538.1
RefSeq - NP_001341296.1
RefSeq - NP_001341297.1
RefSeq - NP_001341298.1
RefSeq - NP_001341299.1
RefSeq - NP_056934.2
RefSeq - NP_075593.1
RefSeq - NP_075594.1
RefSeq - NP_075598.2
RefSeq - 1370512065
RefSeq - 291327489
RefSeq - 291327491
RefSeq - 291327493
RefSeq - 291327495
RefSeq - 291327497
RefSeq - 578815231
RefSeq - 578815233
RefSeq - 578815239
RefSeq - 578815245
RefSeq - 578815247
RefSeq - XR_001745496.1
RefSeq - NM_001174063.1
RefSeq - NM_001174064.1
RefSeq - NM_001174065.1
RefSeq - NM_001174066.1
RefSeq - NM_001174067.1
RefSeq - NM_001354367.1
RefSeq - NM_001354368.1
RefSeq - NM_001354369.1
RefSeq - NM_001354370.1
RefSeq - NM_015850.3
RefSeq - NM_023105.2
RefSeq - NM_023106.2
RefSeq - NM_023107.2
RefSeq - NM_023108.2
RefSeq - NM_023109.1
RefSeq - NM_023110.2
RefSeq - NM_023111.2
RefSeq - NM_032191.1
RefSeq - XM_006716303.3
RefSeq - XM_006716304.1
RefSeq - XM_006716307.1
RefSeq - XM_006716310.3
RefSeq - XM_006716311.1
RefSeq - XM_006716312.2
RefSeq - XM_006716314.2
RefSeq - XM_011544443.2
RefSeq - XM_011544444.1
RefSeq - XM_011544445.2
RefSeq - XM_011544446.2
RefSeq - XM_011544447.2
RefSeq - XM_011544448.1
RefSeq - XM_011544449.1
RefSeq - XM_011544450.2
RefSeq - XM_011544451.1
RefSeq - XM_011544452.2
RefSeq - XM_017013219.1
RefSeq - XM_017013220.1
RefSeq - XM_017013221.1
RefSeq - XM_017013222.2
RefSeq - XM_017013224.2
RefSeq - XM_017013225.2
RefSeq - XM_017013226.1
RefSeq - XM_017013227.1
RefSeq - XM_017013229.2
RefSeq - XM_017013230.1
RefSeq - XM_017013231.1
RefSeq - XM_024447097.1
RefSeq - XR_001745495.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000077782 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001759 organ induction IEA
 biological_processGO:0001764 neuron migration TAS
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IEA
 biological_processGO:0002062 chondrocyte differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation NAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007417 central nervous system development IBA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010518 positive regulation of phospholipase activity TAS
 biological_processGO:0010863 positive regulation of phospholipase C activity IDA
 biological_processGO:0010966 regulation of phosphate transport IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling TAS
 biological_processGO:0016477 cell migration TAS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0021847 ventricular zone neuroblast division IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development IEA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0042473 outer ear morphogenesis IEA
 biological_processGO:0042474 middle ear morphogenesis IEA
 biological_processGO:0043009 chordate embryonic development TAS
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IGI
 biological_processGO:0045595 regulation of cell differentiation TAS
 biological_processGO:0045666 positive regulation of neuron differentiation IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling TAS
 biological_processGO:0048339 paraxial mesoderm development IEA
 biological_processGO:0048378 regulation of lateral mesodermal cell fate specification IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048705 skeletal system morphogenesis TAS
 biological_processGO:0048762 mesenchymal cell differentiation IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0060045 positive regulation of cardiac muscle cell proliferation IEA
 biological_processGO:0060117 auditory receptor cell development IEA
 biological_processGO:0060445 branching involved in salivary gland morphogenesis IEA
 biological_processGO:0060484 lung-associated mesenchyme development IEA
 biological_processGO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0070640 vitamin D3 metabolic process IEA
 biological_processGO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0090272 negative regulation of fibroblast growth factor production IEA
 biological_processGO:1903465 positive regulation of mitotic cell cycle DNA replication IEA
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation IGI
 biological_processGO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor IDA
 biological_processGO:2000830 positive regulation of parathyroid hormone secretion IEA
 biological_processGO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005007 fibroblast growth factor-activated receptor activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0017134 fibroblast growth factor binding IDA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0090722 receptor-receptor interaction IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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