2263


Homo sapiens (NCBI)

Features
Gene ID: 2263
  
Biological name :
  
Synonyms : BBDS|BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25 / FGFR2 / fibroblast growth factor receptor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203638_s_at (Human Genome U133 Plus 2.0 Array)   203639_s_at (Human Genome U133 Plus 2.0 Array)   208225_at (Human Genome U133 Plus 2.0 Array)   208228_s_at (Human Genome U133 Plus 2.0 Array)   208229_at (Human Genome U133 Plus 2.0 Array)   208234_x_at (Human Genome U133 Plus 2.0 Array)   211398_at (Human Genome U133 Plus 2.0 Array)   211399_at (Human Genome U133 Plus 2.0 Array)   211400_at (Human Genome U133 Plus 2.0 Array)   211401_s_at (Human Genome U133 Plus 2.0 Array)   240913_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 222144241
RefSeq - 1002341835
RefSeq - 1034567208
RefSeq - 1034567210
RefSeq - 1034567216
RefSeq - 1034567218
RefSeq - 13186243
RefSeq - 1370456685
RefSeq - 1370456687
RefSeq - 1370456689
RefSeq - 1370456691
RefSeq - 1370456693
RefSeq - 1370456697
RefSeq - 221316638
RefSeq - 221316639
RefSeq - 222144231
RefSeq - 222144233
RefSeq - 222144235
RefSeq - 222144237
RefSeq - 222144239
RefSeq - 1002341823
RefSeq - 222144244
RefSeq - 578819115
RefSeq - 578819119
RefSeq - NC_000010.11
RefSeq - NG_012449.2
RefSeq - NP_000132.3
RefSeq - NP_001138385.1
RefSeq - NP_001138386.1
RefSeq - NP_001138387.1
RefSeq - NP_001138388.1
RefSeq - NP_001138389.1
RefSeq - NP_001138390.1
RefSeq - NP_001138391.1
RefSeq - NP_001307583.1
RefSeq - NP_001307587.1
RefSeq - NP_075259.4
RefSeq - NP_075418.1
RefSeq - XP_006717771.1
RefSeq - XP_006717773.1
RefSeq - XP_016871409.1
RefSeq - XP_016871410.1
RefSeq - XP_016871413.1
RefSeq - XP_016871414.1
RefSeq - XP_024303655.1
RefSeq - XP_024303656.1
RefSeq - XP_024303657.1
RefSeq - XP_024303658.1
RefSeq - XP_024303659.1
RefSeq - XP_024303660.1
RefSeq - XM_017015924.2
RefSeq - XM_017015925.2
RefSeq - XM_024447887.1
RefSeq - XM_024447888.1
RefSeq - XM_024447889.1
RefSeq - XM_024447890.1
RefSeq - XM_024447891.1
RefSeq - XM_024447892.1
RefSeq - NR_073009.1
RefSeq - NM_000141.4
RefSeq - NM_001144913.1
RefSeq - NM_001144914.1
RefSeq - NM_001144915.1
RefSeq - NM_001144916.1
RefSeq - NM_001144917.1
RefSeq - NM_001144918.1
RefSeq - NM_001144919.1
RefSeq - NM_001320654.1
RefSeq - NM_001320658.1
RefSeq - NM_022970.3
RefSeq - NM_022971.1
RefSeq - NM_022972.1
RefSeq - NM_022973.1
RefSeq - NM_022974.1
RefSeq - NM_022975.2
RefSeq - NM_022976.1
RefSeq - NM_023028.1
RefSeq - NM_023029.2
RefSeq - NM_023030.1
RefSeq - XM_006717708.3
RefSeq - XM_006717710.4
RefSeq - XM_017015920.2
RefSeq - XM_017015921.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000066468 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001525 angiogenesis ISS
 biological_processGO:0001657 ureteric bud development ISS
 biological_processGO:0001701 in utero embryonic development ISS
 biological_processGO:0001837 epithelial to mesenchymal transition IEA
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation ISS
 biological_processGO:0003148 outflow tract septum morphogenesis ISS
 biological_processGO:0003149 membranous septum morphogenesis ISS
 biological_processGO:0003416 endochondral bone growth IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007267 cell-cell signaling ISS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0008589 regulation of smoothened signaling pathway ISS
 biological_processGO:0009791 post-embryonic development ISS
 biological_processGO:0009880 embryonic pattern specification ISS
 biological_processGO:0009887 animal organ morphogenesis ISS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010453 regulation of cell fate commitment ISS
 biological_processGO:0010518 positive regulation of phospholipase activity IMP
 biological_processGO:0016331 morphogenesis of embryonic epithelium ISS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0021769 orbitofrontal cortex development ISS
 biological_processGO:0021847 ventricular zone neuroblast division ISS
 biological_processGO:0021860 pyramidal neuron development ISS
 biological_processGO:0022612 gland morphogenesis ISS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway ISS
 biological_processGO:0030282 bone mineralization ISS
 biological_processGO:0030324 lung development ISS
 biological_processGO:0030855 epithelial cell differentiation ISS
 biological_processGO:0030901 midbrain development ISS
 biological_processGO:0030916 otic vesicle formation ISS
 biological_processGO:0031069 hair follicle morphogenesis ISS
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032808 lacrimal gland development ISS
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0033688 regulation of osteoblast proliferation TAS
 biological_processGO:0035264 multicellular organism growth ISS
 biological_processGO:0035265 organ growth ISS
 biological_processGO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow ISS
 biological_processGO:0035603 fibroblast growth factor receptor signaling pathway involved in hemopoiesis ISS
 biological_processGO:0035604 fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow ISS
 biological_processGO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development ISS
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0040014 regulation of multicellular organism growth ISS
 biological_processGO:0040036 regulation of fibroblast growth factor receptor signaling pathway ISS
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042472 inner ear morphogenesis ISS
 biological_processGO:0042476 odontogenesis ISS
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0045165 cell fate commitment ISS
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045667 regulation of osteoblast differentiation TAS
 biological_processGO:0045787 positive regulation of cell cycle ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048286 lung alveolus development ISS
 biological_processGO:0048333 mesodermal cell differentiation IEA
 biological_processGO:0048557 embryonic digestive tract morphogenesis ISS
 biological_processGO:0048562 embryonic organ morphogenesis ISS
 biological_processGO:0048565 digestive tract development ISS
 biological_processGO:0048568 embryonic organ development ISS
 biological_processGO:0048608 reproductive structure development ISS
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0048705 skeletal system morphogenesis TAS
 biological_processGO:0048730 epidermis morphogenesis ISS
 biological_processGO:0048755 branching morphogenesis of a nerve ISS
 biological_processGO:0048762 mesenchymal cell differentiation ISS
 biological_processGO:0050679 positive regulation of epithelial cell proliferation ISS
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0051150 regulation of smooth muscle cell differentiation ISS
 biological_processGO:0051781 positive regulation of cell division ISS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis ISS
 biological_processGO:0060045 positive regulation of cardiac muscle cell proliferation ISS
 biological_processGO:0060174 limb bud formation ISS
 biological_processGO:0060348 bone development ISS
 biological_processGO:0060349 bone morphogenesis ISS
 biological_processGO:0060442 branching involved in prostate gland morphogenesis ISS
 biological_processGO:0060445 branching involved in salivary gland morphogenesis ISS
 biological_processGO:0060449 bud elongation involved in lung branching ISS
 biological_processGO:0060463 lung lobe morphogenesis ISS
 biological_processGO:0060484 lung-associated mesenchyme development ISS
 biological_processGO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis ISS
 biological_processGO:0060512 prostate gland morphogenesis ISS
 biological_processGO:0060523 prostate epithelial cord elongation ISS
 biological_processGO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ISS
 biological_processGO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development ISS
 biological_processGO:0060595 fibroblast growth factor receptor signaling pathway involved in mammary gland specification ISS
 biological_processGO:0060601 lateral sprouting from an epithelium ISS
 biological_processGO:0060615 mammary gland bud formation ISS
 biological_processGO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis ISS
 biological_processGO:0060667 branch elongation involved in salivary gland morphogenesis ISS
 biological_processGO:0060670 branching involved in labyrinthine layer morphogenesis ISS
 biological_processGO:0060687 regulation of branching involved in prostate gland morphogenesis ISS
 biological_processGO:0060688 regulation of morphogenesis of a branching structure ISS
 biological_processGO:0060915 mesenchymal cell differentiation involved in lung development ISS
 biological_processGO:0060916 mesenchymal cell proliferation involved in lung development ISS
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0060076 excitatory synapse ISS
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005007 fibroblast growth factor-activated receptor activity NAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0017134 fibroblast growth factor binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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