2264


Homo sapiens (NCBI)

Features
Gene ID: 2264
  
Biological name :
  
Synonyms : CD334|JTK2|TKF / FGFR4 / fibroblast growth factor receptor 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1554961_at (Human Genome U133 Plus 2.0 Array)   1554962_a_at (Human Genome U133 Plus 2.0 Array)   204579_at (Human Genome U133 Plus 2.0 Array)   211237_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1238789392
RefSeq - 47524173
RefSeq - 47524175
RefSeq - 47524177
RefSeq - 634743314
RefSeq - NC_000005.10
RefSeq - NG_012067.1
RefSeq - NP_001278909.1
RefSeq - NP_001341913.1
RefSeq - NP_002002.3
RefSeq - NP_075252.2
RefSeq - NP_998812.1
RefSeq - NM_001291980.1
RefSeq - NM_001354984.1
RefSeq - NM_002011.4
RefSeq - NM_022963.3
RefSeq - NM_213647.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000160867 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001525 angiogenesis IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007417 central nervous system development IBA
 biological_processGO:0008284 positive regulation of cell proliferation IGI
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010715 regulation of extracellular matrix disassembly IMP
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0019216 regulation of lipid metabolic process ISS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0036092 phosphatidylinositol-3-phosphate biosynthetic process IEA
 biological_processGO:0042593 glucose homeostasis ISS
 biological_processGO:0042632 cholesterol homeostasis ISS
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043085 positive regulation of catalytic activity IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045862 positive regulation of proteolysis IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0055062 phosphate ion homeostasis ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070857 regulation of bile acid biosynthetic process IMP
 biological_processGO:1903412 response to bile acid IMP
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0030133 transport vesicle IDA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005007 fibroblast growth factor-activated receptor activity IGI
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0016303 1-phosphatidylinositol-3-kinase activity TAS
 molecular_functionGO:0017134 fibroblast growth factor binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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