2321


Homo sapiens (NCBI)

Features
Gene ID: 2321
  
Biological name :
  
Synonyms : FLT1 / FLT|FLT-1|VEGFR-1|VEGFR1 / fms related tyrosine kinase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204406_at (Human Genome U133 Plus 2.0 Array)   210287_s_at (Human Genome U133 Plus 2.0 Array)   222033_s_at (Human Genome U133 Plus 2.0 Array)   226497_s_at (Human Genome U133 Plus 2.0 Array)   226498_at (Human Genome U133 Plus 2.0 Array)   232809_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034584130
RefSeq - 156104876
RefSeq - 229892220
RefSeq - 229892300
RefSeq - 229892302
RefSeq - 767977511
RefSeq - NC_000013.11
RefSeq - NG_012003.1
RefSeq - NP_001153392.1
RefSeq - NP_001153502.1
RefSeq - NP_001153503.1
RefSeq - NP_002010.2
RefSeq - XP_011533316.1
RefSeq - XP_016875974.1
RefSeq - NM_001159920.1
RefSeq - NM_001160030.1
RefSeq - NM_001160031.1
RefSeq - NM_002019.4
RefSeq - XM_011535014.1
RefSeq - XM_017020485.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000102755 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0002548 monocyte chemotaxis IDA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010863 positive regulation of phospholipase C activity IMP
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway IDA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IDA
 biological_processGO:0036323 vascular endothelial growth factor receptor-1 signaling pathway IDA
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IEA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043406 positive regulation of MAP kinase activity IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IMP
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048514 blood vessel morphogenesis ISS
 biological_processGO:0048598 embryonic morphogenesis ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:1905563 negative regulation of vascular endothelial cell proliferation IGI
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0036326 VEGF-A-activated receptor activity IDA
 molecular_functionGO:0036327 VEGF-B-activated receptor activity IDA
 molecular_functionGO:0036332 placental growth factor-activated receptor activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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