2322


Homo sapiens (NCBI)

Features
Gene ID: 2322
  
Biological name :
  
Synonyms : CD135|FLK-2|FLK2|STK1 / FLT3 / fms related tyrosine kinase 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206674_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034584133
RefSeq - 1034584135
RefSeq - 1034584139
RefSeq - 1034584141
RefSeq - 121114304
RefSeq - 767977513
RefSeq - 767977517
RefSeq - 767977519
RefSeq - NC_000013.11
RefSeq - NG_007066.1
RefSeq - NP_004110.2
RefSeq - XP_011533317.1
RefSeq - XP_011533319.1
RefSeq - XP_011533320.1
RefSeq - XP_016875975.1
RefSeq - XP_016875976.1
RefSeq - XP_016875977.1
RefSeq - XP_016875978.1
RefSeq - XM_017020488.1
RefSeq - NM_004119.2
RefSeq - XM_017020489.1
RefSeq - NR_130706.1
RefSeq - XM_011535015.2
RefSeq - XM_011535017.2
RefSeq - XM_011535018.2
RefSeq - XM_017020486.1
RefSeq - XM_017020487.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000122025 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001776 leukocyte homeostasis ISS
 biological_processGO:0002318 myeloid progenitor cell differentiation ISS
 biological_processGO:0002328 pro-B cell differentiation ISS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010243 response to organonitrogen compound IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling TAS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030097 hemopoiesis IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030183 B cell differentiation ISS
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035726 common myeloid progenitor cell proliferation ISS
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein TAS
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043406 positive regulation of MAP kinase activity TAS
 biological_processGO:0043410 positive regulation of MAPK cascade TAS
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity TAS
 biological_processGO:0046651 lymphocyte proliferation ISS
 biological_processGO:0046777 protein autophosphorylation TAS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:0071385 cellular response to glucocorticoid stimulus IEA
 biological_processGO:0097028 dendritic cell differentiation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0004896 cytokine receptor activity ISS
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0035259 glucocorticoid receptor binding IEA
 molecular_functionGO:0042803 protein homodimerization activity TAS
 molecular_functionGO:0043621 protein self-association IMP
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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