24088


Mus musculus (NCBI)

Features
Gene ID: 24088
  
Biological name :
  
Synonyms : Ly105 / Tlr2 / toll-like receptor 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1419132_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568922750
RefSeq - XP_006501523.1
RefSeq - NC_000069.6
RefSeq - 158749638
RefSeq - NP_036035.3
RefSeq - NM_011905.3
RefSeq - XM_006501460.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000027995 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation ISO
 biological_processGO:0001775 cell activation ISO
 biological_processGO:0002224 toll-like receptor signaling pathway ISO
 biological_processGO:0002237 response to molecule of bacterial origin IEA
 biological_processGO:0002238 response to molecule of fungal origin IMP
 biological_processGO:0002374 cytokine secretion involved in immune response ISO
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002687 positive regulation of leukocyte migration IMP
 biological_processGO:0002730 regulation of dendritic cell cytokine production IDA
 biological_processGO:0002752 cell surface pattern recognition receptor signaling pathway IMP
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway IGI
 biological_processGO:0006691 leukotriene metabolic process ISO
 biological_processGO:0006954 inflammatory response ISO
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007252 I-kappaB phosphorylation ISO
 biological_processGO:0007612 learning IGI
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0014005 microglia development IGI
 biological_processGO:0030177 positive regulation of Wnt signaling pathway ISO
 biological_processGO:0030837 negative regulation of actin filament polymerization IGI
 biological_processGO:0032289 central nervous system myelin formation ISO
 biological_processGO:0032493 response to bacterial lipoprotein ISO
 biological_processGO:0032494 response to peptidoglycan IMP
 biological_processGO:0032613 interleukin-10 production ISO
 biological_processGO:0032640 tumor necrosis factor production IGI
 biological_processGO:0032695 negative regulation of interleukin-12 production IMP
 biological_processGO:0032700 negative regulation of interleukin-17 production IMP
 biological_processGO:0032722 positive regulation of chemokine production ISO
 biological_processGO:0032728 positive regulation of interferon-beta production IDA
 biological_processGO:0032733 positive regulation of interleukin-10 production ISO
 biological_processGO:0032735 positive regulation of interleukin-12 production IDA
 biological_processGO:0032741 positive regulation of interleukin-18 production IDA
 biological_processGO:0032755 positive regulation of interleukin-6 production ISO
 biological_processGO:0032757 positive regulation of interleukin-8 production ISO
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IMP
 biological_processGO:0034123 positive regulation of toll-like receptor signaling pathway ISO
 biological_processGO:0034134 toll-like receptor 2 signaling pathway IEA
 biological_processGO:0042495 detection of triacyl bacterial lipopeptide ISO
 biological_processGO:0042496 detection of diacyl bacterial lipopeptide ISO
 biological_processGO:0042535 positive regulation of tumor necrosis factor biosynthetic process IMP
 biological_processGO:0042892 chloramphenicol transport IMP
 biological_processGO:0044130 negative regulation of growth of symbiont in host IMP
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046209 nitric oxide metabolic process ISO
 biological_processGO:0048714 positive regulation of oligodendrocyte differentiation ISO
 biological_processGO:0050707 regulation of cytokine secretion IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IGI
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IGI
 biological_processGO:0050729 positive regulation of inflammatory response IGI
 biological_processGO:0050765 negative regulation of phagocytosis IMP
 biological_processGO:0050830 defense response to Gram-positive bacterium ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IDA
 biological_processGO:0051964 negative regulation of synapse assembly IGI
 biological_processGO:0052063 induction by symbiont of defense-related host nitric oxide production IMP
 biological_processGO:0060907 positive regulation of macrophage cytokine production IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070542 response to fatty acid ISO
 biological_processGO:0071221 cellular response to bacterial lipopeptide TAS
 biological_processGO:0071223 cellular response to lipoteichoic acid ISO
 biological_processGO:0071224 cellular response to peptidoglycan IMP
 biological_processGO:0071346 cellular response to interferon-gamma ISO
 biological_processGO:0071726 cellular response to diacyl bacterial lipopeptide ISO
 biological_processGO:0071727 cellular response to triacyl bacterial lipopeptide ISO
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling ISO
 biological_processGO:1903974 positive regulation of cellular response to macrophage colony-stimulating factor stimulus ISO
 biological_processGO:1904417 positive regulation of xenophagy IMP
 biological_processGO:1904469 positive regulation of tumor necrosis factor secretion IGI
 biological_processGO:2000484 positive regulation of interleukin-8 secretion ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex ISO
 cellular_componentGO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex IPI
 cellular_componentGO:0042995 cell projection ISO
 cellular_componentGO:0044297 cell body ISO
 cellular_componentGO:0045121 membrane raft ISO
 molecular_functionGO:0001530 lipopolysaccharide binding ISO
 molecular_functionGO:0001540 amyloid-beta binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008329 signaling pattern recognition receptor activity ISO
 molecular_functionGO:0035325 Toll-like receptor binding ISO
 molecular_functionGO:0042497 triacyl lipopeptide binding ISO
 molecular_functionGO:0042498 diacyl lipopeptide binding IDA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042834 peptidoglycan binding ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0070891 lipoteichoic acid binding IDA
 molecular_functionGO:0071723 lipopeptide binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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