Manteia

25

Homo sapiens (NCBI)

Features

Gene ID:	25

Biological name :

Synonyms :	ABL1 / ABL\|CHDSKM\|JTK7\|bcr/abl\|c-ABL\|c-ABL1\|p150\|v-abl / ABL proto-oncogene 1, non-receptor tyrosine kinase

Possible biological names infered from orthology :

Species:	Homo sapiens (NCBI)

Chr. number:
Strand:
Band:
Gene start:
Gene end:

Corresponding Affymetrix probe sets:	202123_s_at (Human Genome U133 Plus 2.0 Array)

Cross references:	RefSeq - 62362412 RefSeq - 62362414 RefSeq - NC_000009.12 RefSeq - NG_012034.1 RefSeq - NP_005148.2 RefSeq - NP_009297.2 RefSeq - NM_005157.5 RefSeq - NM_007313.2

See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000097007 to get all the annotations available for this gene.

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000278	mitotic cell cycle	TAS
biological_process	GO:0001843	neural tube closure	IEA
biological_process	GO:0001922	B-1 B cell homeostasis	IEA
biological_process	GO:0001934	positive regulation of protein phosphorylation	IMP
biological_process	GO:0002322	B cell proliferation involved in immune response	IEA
biological_process	GO:0002333	transitional one stage B cell differentiation	IEA
biological_process	GO:0006298	mismatch repair	TAS
biological_process	GO:0006355	regulation of transcription, DNA-templated	TAS
biological_process	GO:0006464	cellular protein modification process	NAS
biological_process	GO:0006468	protein phosphorylation	IMP
biological_process	GO:0006914	autophagy	IEA
biological_process	GO:0006974	cellular response to DNA damage stimulus	IDA
biological_process	GO:0006975	DNA damage induced protein phosphorylation	IDA
biological_process	GO:0006979	response to oxidative stress	IGI
biological_process	GO:0007050	cell cycle arrest	TAS
biological_process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA
biological_process	GO:0007173	epidermal growth factor receptor signaling pathway	IEA
biological_process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IMP
biological_process	GO:0007229	integrin-mediated signaling pathway	IMP
biological_process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	TAS
biological_process	GO:0009791	post-embryonic development	IEA
biological_process	GO:0010506	regulation of autophagy	TAS
biological_process	GO:0010595	positive regulation of endothelial cell migration	IMP
biological_process	GO:0018108	peptidyl-tyrosine phosphorylation	TAS
biological_process	GO:0021587	cerebellum morphogenesis	IEA
biological_process	GO:0022408	negative regulation of cell-cell adhesion	IEA
biological_process	GO:0030035	microspike assembly	IEA
biological_process	GO:0030036	actin cytoskeleton organization	ISS
biological_process	GO:0030100	regulation of endocytosis	TAS
biological_process	GO:0030154	cell differentiation	IBA
biological_process	GO:0030155	regulation of cell adhesion	TAS
biological_process	GO:0030514	negative regulation of BMP signaling pathway	IEA
biological_process	GO:0030516	regulation of axon extension	IMP
biological_process	GO:0031113	regulation of microtubule polymerization	IMP
biological_process	GO:0032489	regulation of Cdc42 protein signal transduction	IMP
biological_process	GO:0032956	regulation of actin cytoskeleton organization	IMP
biological_process	GO:0033690	positive regulation of osteoblast proliferation	IEA
biological_process	GO:0034446	substrate adhesion-dependent cell spreading	IEA
biological_process	GO:0034599	cellular response to oxidative stress	TAS
biological_process	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	IMP
biological_process	GO:0038083	peptidyl-tyrosine autophosphorylation	IMP
biological_process	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	TAS
biological_process	GO:0038189	neuropilin signaling pathway	IMP
biological_process	GO:0042127	regulation of cell proliferation	IBA
biological_process	GO:0042770	signal transduction in response to DNA damage	IDA
biological_process	GO:0042981	regulation of apoptotic process	IBA
biological_process	GO:0043065	positive regulation of apoptotic process	IDA
biological_process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IEA
biological_process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IEA
biological_process	GO:0043542	endothelial cell migration	IMP
biological_process	GO:0045087	innate immune response	IBA
biological_process	GO:0045184	establishment of protein localization	IMP
biological_process	GO:0045580	regulation of T cell differentiation	ISS
biological_process	GO:0045930	negative regulation of mitotic cell cycle	IEA
biological_process	GO:0045931	positive regulation of mitotic cell cycle	IEA
biological_process	GO:0046632	alpha-beta T cell differentiation	IEA
biological_process	GO:0046777	protein autophosphorylation	IDA
biological_process	GO:0048536	spleen development	IEA
biological_process	GO:0048538	thymus development	IEA
biological_process	GO:0048668	collateral sprouting	IEA
biological_process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA
biological_process	GO:0050798	activated T cell proliferation	IEA
biological_process	GO:0050853	B cell receptor signaling pathway	IEA
biological_process	GO:0050885	neuromuscular process controlling balance	IEA
biological_process	GO:0051149	positive regulation of muscle cell differentiation	TAS
biological_process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	IEA
biological_process	GO:0051353	positive regulation of oxidoreductase activity	IDA
biological_process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	TAS
biological_process	GO:0051496	positive regulation of stress fiber assembly	IMP
biological_process	GO:0051882	mitochondrial depolarization	TAS
biological_process	GO:0051894	positive regulation of focal adhesion assembly	IMP
biological_process	GO:0060020	Bergmann glial cell differentiation	IEA
biological_process	GO:0060563	neuroepithelial cell differentiation	IEA
biological_process	GO:0070301	cellular response to hydrogen peroxide	IDA
biological_process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IEA
biological_process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IEA
biological_process	GO:0071222	cellular response to lipopolysaccharide	IEA
biological_process	GO:0071901	negative regulation of protein serine/threonine kinase activity	IDA
biological_process	GO:0072358	cardiovascular system development	IEA
biological_process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	IEA
biological_process	GO:0090135	actin filament branching	IEA
biological_process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	IMP
biological_process	GO:1900042	positive regulation of interleukin-2 secretion	IEA
biological_process	GO:1900272	negative regulation of long-term synaptic potentiation	ISS
biological_process	GO:1900275	negative regulation of phospholipase C activity	IMP
biological_process	GO:1901216	positive regulation of neuron death	IEA
biological_process	GO:1902036	regulation of hematopoietic stem cell differentiation	TAS
biological_process	GO:1902715	positive regulation of interferon-gamma secretion	IEA
biological_process	GO:1903053	regulation of extracellular matrix organization	IEA
biological_process	GO:1903351	cellular response to dopamine	TAS
biological_process	GO:1904528	positive regulation of microtubule binding	IMP
biological_process	GO:1904531	positive regulation of actin filament binding	IMP
biological_process	GO:1905244	regulation of modification of synaptic structure	ISS
biological_process	GO:1905555	positive regulation blood vessel branching	IEA
biological_process	GO:1990051	activation of protein kinase C activity	IDA
biological_process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	IEA
biological_process	GO:2000145	regulation of cell motility	TAS
biological_process	GO:2000249	regulation of actin cytoskeleton reorganization	TAS
biological_process	GO:2000251	positive regulation of actin cytoskeleton reorganization	IMP
biological_process	GO:2000352	negative regulation of endothelial cell apoptotic process	IEA
biological_process	GO:2000773	negative regulation of cellular senescence	IEA
biological_process	GO:2001020	regulation of response to DNA damage stimulus	IDA
cellular_component	GO:0005634	nucleus	TAS
cellular_component	GO:0005654	nucleoplasm	TAS
cellular_component	GO:0005730	nucleolus	IDA
cellular_component	GO:0005737	cytoplasm	TAS
cellular_component	GO:0005739	mitochondrion	NAS
cellular_component	GO:0005829	cytosol	TAS
cellular_component	GO:0015629	actin cytoskeleton	TAS
cellular_component	GO:0016604	nuclear body	IDA
cellular_component	GO:0030425	dendrite	ISS
cellular_component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	IBA
cellular_component	GO:0031252	cell leading edge	IEA
cellular_component	GO:0031965	nuclear membrane	IEA
cellular_component	GO:0032991	protein-containing complex	IPI
cellular_component	GO:0043025	neuronal cell body	ISS
cellular_component	GO:0048471	perinuclear region of cytoplasm	IDA
cellular_component	GO:0098794	postsynapse	TAS
molecular_function	GO:0000287	magnesium ion binding	IDA
molecular_function	GO:0001784	phosphotyrosine residue binding	IPI
molecular_function	GO:0003677	DNA binding	NAS
molecular_function	GO:0003785	actin monomer binding	TAS
molecular_function	GO:0004515	nicotinate-nucleotide adenylyltransferase activity	TAS
molecular_function	GO:0004672	protein kinase activity	IMP
molecular_function	GO:0004713	protein tyrosine kinase activity	TAS
molecular_function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IMP
molecular_function	GO:0005080	protein kinase C binding	IPI
molecular_function	GO:0005102	signaling receptor binding	IBA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0005524	ATP binding	IDA
molecular_function	GO:0008022	protein C-terminus binding	IPI
molecular_function	GO:0016301	kinase activity	IMP
molecular_function	GO:0017124	SH3 domain binding	IPI
molecular_function	GO:0019905	syntaxin binding	IPI
molecular_function	GO:0030145	manganese ion binding	IDA
molecular_function	GO:0038191	neuropilin binding	IPI
molecular_function	GO:0042169	SH2 domain binding	IPI
molecular_function	GO:0046875	ephrin receptor binding	ISS
molecular_function	GO:0051015	actin filament binding	IEA
molecular_function	GO:0051019	mitogen-activated protein kinase binding	IPI
molecular_function	GO:0070064	proline-rich region binding	IPI

Pathways (from Reactome)

Pathway description

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr