2534


Homo sapiens (NCBI)

Features
Gene ID: 2534
  
Biological name :
  
Synonyms : FYN / FYN proto-oncogene, Src family tyrosine kinase / SLK|SYN|p59-FYN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 210105_s_at (Human Genome U133 Plus 2.0 Array)   212486_s_at (Human Genome U133 Plus 2.0 Array)   216033_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016866144.1
RefSeq - 1034649571
RefSeq - 1034649573
RefSeq - 1034649575
RefSeq - 1034649577
RefSeq - 1034649581
RefSeq - 23510362
RefSeq - 23510364
RefSeq - 4503823
RefSeq - 530383513
RefSeq - 530383517
RefSeq - NC_000006.12
RefSeq - NP_002028.1
RefSeq - NP_694592.1
RefSeq - NP_694593.1
RefSeq - XP_005266947.1
RefSeq - XP_005266949.1
RefSeq - XP_016866139.1
RefSeq - XP_016866140.1
RefSeq - XP_016866141.1
RefSeq - XP_016866142.1
RefSeq - XP_016866143.1
RefSeq - 1034649569
RefSeq - XM_017010652.1
RefSeq - NM_001242779.1
RefSeq - NM_002037.5
RefSeq - NM_153047.3
RefSeq - NM_153048.3
RefSeq - XM_017010653.1
RefSeq - XM_017010654.1
RefSeq - XM_017010655.2
RefSeq - XM_005266890.4
RefSeq - XM_005266892.4
RefSeq - XM_017010650.1
RefSeq - XM_017010651.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000010810 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000304 response to singlet oxygen ISS
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0003015 heart process IGI
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006816 calcium ion transport NAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0007612 learning TAS
 biological_processGO:0007631 feeding behavior TAS
 biological_processGO:0008360 regulation of cell shape ISS
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010730 negative regulation of hydrogen peroxide biosynthetic process ISS
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0031295 T cell costimulation TAS
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction TAS
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IEA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0042110 T cell activation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0042542 response to hydrogen peroxide ISS
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0048813 dendrite morphogenesis IEA
 biological_processGO:0050690 regulation of defense response to virus by virus TAS
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation ISS
 biological_processGO:0050798 activated T cell proliferation IEA
 biological_processGO:0050852 T cell receptor signaling pathway IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0050966 detection of mechanical stimulus involved in sensory perception of pain IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0071375 cellular response to peptide hormone stimulus IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0090314 positive regulation of protein targeting to membrane ISS
 biological_processGO:0097062 dendritic spine maintenance TAS
 biological_processGO:1900182 positive regulation of protein localization to nucleus IEA
 biological_processGO:1900449 regulation of glutamate receptor signaling pathway ISS
 biological_processGO:1901216 positive regulation of neuron death ISS
 biological_processGO:1902951 negative regulation of dendritic spine maintenance ISS
 biological_processGO:1903202 negative regulation of oxidative stress-induced cell death ISS
 biological_processGO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity TAS
 biological_processGO:1904645 response to amyloid-beta ISS
 biological_processGO:1905232 cellular response to L-glutamate ISS
 biological_processGO:1905430 cellular response to glycine ISS
 biological_processGO:1905477 positive regulation of protein localization to membrane TAS
 biological_processGO:1905664 regulation of calcium ion import across plasma membrane ISS
 biological_processGO:2001056 positive regulation of cysteine-type endopeptidase activity ISS
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0044297 cell body ISS
 cellular_componentGO:0045121 membrane raft TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum ISS
 cellular_componentGO:0097386 glial cell projection ISS
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity NAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031802 type 5 metabotropic glutamate receptor binding ISS
 molecular_functionGO:0042608 T cell receptor binding IEA
 molecular_functionGO:0042609 CD4 receptor binding IEA
 molecular_functionGO:0042610 CD8 receptor binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043014 alpha-tubulin binding ISS
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS
 molecular_functionGO:0048156 tau protein binding TAS
 molecular_functionGO:0051428 peptide hormone receptor binding IEA
 molecular_functionGO:0070851 growth factor receptor binding IPI
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr