26395


Mus musculus (NCBI)

Features
Gene ID: 26395
  
Biological name :
  
Synonyms : Map2k1 / MAPKK1|MEKK1|Mek1|Prkmk1 / mitogen-activated protein kinase kinase 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416351_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6678794
RefSeq - XP_006511259.1
RefSeq - NC_000075.6
RefSeq - 568961539
RefSeq - NP_032953.1
RefSeq - NM_008927.3
RefSeq - XM_006511196.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000004936 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade ISO
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0000278 mitotic cell cycle ISO
 biological_processGO:0001932 regulation of protein phosphorylation IGI
 biological_processGO:0003056 regulation of vascular smooth muscle contraction ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006979 response to oxidative stress ISO
 biological_processGO:0007050 cell cycle arrest ISO
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007507 heart development IGI
 biological_processGO:0008283 cell proliferation ISO
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0010508 positive regulation of autophagy ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISO
 biological_processGO:0021697 cerebellar cortex formation IGI
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030182 neuron differentiation ISO
 biological_processGO:0030216 keratinocyte differentiation IMP
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030878 thyroid gland development IGI
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0032402 melanosome transport ISO
 biological_processGO:0032872 regulation of stress-activated MAPK cascade TAS
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter ISO
 biological_processGO:0034111 negative regulation of homotypic cell-cell adhesion ISO
 biological_processGO:0042593 glucose homeostasis ISO
 biological_processGO:0043547 positive regulation of GTPase activity ISO
 biological_processGO:0045597 positive regulation of cell differentiation IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045933 positive regulation of muscle contraction ISO
 biological_processGO:0046579 positive regulation of Ras protein signal transduction ISO
 biological_processGO:0047496 vesicle transport along microtubule ISO
 biological_processGO:0048313 Golgi inheritance ISO
 biological_processGO:0048538 thymus development IGI
 biological_processGO:0048678 response to axon injury ISO
 biological_processGO:0048679 regulation of axon regeneration IGI
 biological_processGO:0048812 neuron projection morphogenesis ISO
 biological_processGO:0048870 cell motility IMP
 biological_processGO:0050772 positive regulation of axonogenesis IGI
 biological_processGO:0051291 protein heterooligomerization ISO
 biological_processGO:0051384 response to glucocorticoid ISO
 biological_processGO:0060020 Bergmann glial cell differentiation IGI
 biological_processGO:0060324 face development IGI
 biological_processGO:0060425 lung morphogenesis IGI
 biological_processGO:0060440 trachea formation IGI
 biological_processGO:0060502 epithelial cell proliferation involved in lung morphogenesis IGI
 biological_processGO:0060674 placenta blood vessel development IMP
 biological_processGO:0060711 labyrinthine layer development IMP
 biological_processGO:0070328 triglyceride homeostasis ISO
 biological_processGO:0070371 ERK1 and ERK2 cascade ISO
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity ISO
 biological_processGO:0090170 regulation of Golgi inheritance TAS
 biological_processGO:0090398 cellular senescence ISO
 biological_processGO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway ISO
 biological_processGO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA ISO
 biological_processGO:2000641 regulation of early endosome to late endosome transport TAS
 biological_processGO:2001171 positive regulation of ATP biosynthetic process ISO
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005769 early endosome TAS
 cellular_componentGO:0005770 late endosome TAS
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005925 focal adhesion TAS
 cellular_componentGO:0005938 cell cortex ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0032839 dendrite cytoplasm ISO
 cellular_componentGO:0043204 perikaryon ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0004708 MAP kinase kinase activity ISO
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity TAS
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017016 Ras GTPase binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding ISO
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity ISO
 molecular_functionGO:0047485 protein N-terminus binding ISO
 molecular_functionGO:0097110 scaffold protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr