26408


Mus musculus (NCBI)

Features
Gene ID: 26408
  
Biological name :
  
Synonyms : 7420452D20Rik|ASK|ASK1|MAPKKK5|Mekk5 / Map3k5 / mitogen-activated protein kinase kinase kinase 5
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421340_at (Mouse Genome 430 2.0 Array)   1439830_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 171846249
RefSeq - 568965409
RefSeq - NC_000076.6
RefSeq - NP_032606.4
RefSeq - XP_006512802.1
RefSeq - XM_006512739.3
RefSeq - NM_008580.4
RefSeq - XR_001779529.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000071369 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade ISO
 biological_processGO:0000186 activation of MAPKK activity ISO
 biological_processGO:0000187 activation of MAPK activity IDA
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007254 JNK cascade ISO
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress ISO
 biological_processGO:0010666 positive regulation of cardiac muscle cell apoptotic process ISO
 biological_processGO:0010941 regulation of cell death IGI
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0034198 cellular response to amino acid starvation ISO
 biological_processGO:0034976 response to endoplasmic reticulum stress ISO
 biological_processGO:0038066 p38MAPK cascade IEP
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0043507 positive regulation of JUN kinase activity ISO
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045663 positive regulation of myoblast differentiation IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0051403 stress-activated MAPK cascade ISO
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
 biological_processGO:0070301 cellular response to hydrogen peroxide ISO
 biological_processGO:0097300 programmed necrotic cell death IMP
 biological_processGO:1900745 positive regulation of p38MAPK cascade ISO
 biological_processGO:1901216 positive regulation of neuron death ISO
 biological_processGO:1902170 cellular response to reactive nitrogen species IMP
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation ISO
 cellular_componentGO:0005622 intracellular IEP
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:1902911 protein kinase complex ISO
 cellular_componentGO:1990604 IRE1-TRAF2-ASK1 complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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