26524


Homo sapiens (NCBI)
proteinregulationsignalingbindingcellphosphorylationpathwayserinethreoninekinaseactivitygstransitionmitoticcyclehormone-mediatedpeptidyl-serinehippointracellularsignaltransductionapoptoticprocesscyclin-dependentorgangrowthdivisioncanonicalwnt

Features
Gene ID: 26524
  
Biological name :
  
Synonyms : KPM / large tumor suppressor kinase 2 / LATS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 223379_s_at (Human Genome U133 Plus 2.0 Array)   223380_s_at (Human Genome U133 Plus 2.0 Array)   227013_at (Human Genome U133 Plus 2.0 Array)   230348_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034584287
RefSeq - 1034584289
RefSeq - 126507091
RefSeq - 530402269
RefSeq - 767977579
RefSeq - NC_000013.11
RefSeq - NP_055387.2
RefSeq - XP_005266399.1
RefSeq - XP_011533344.1
RefSeq - XP_016876030.1
RefSeq - XP_016876031.1
RefSeq - NM_014572.2
RefSeq - XM_017020542.1
RefSeq - XM_005266342.1
RefSeq - XM_011535042.2
RefSeq - XM_017020541.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000150457 to get all the annotations available for this gene.


Gene Ontology (GO)
cell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclenitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell deathregulation of molecular functiondevelopmental growthcell divisioncell cyclecell cyclenitrogen cnitrogen compound metabolic processcellular mcellular metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processcell commucell communicationresponse tresponse to endogenous stimulusresponse tresponse to chemicalcellular rcellular response to stimuluscell deathcell deathregulationregulation of molecular functiondevelopmendevelopmental growthcell diviscell division
catalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activity, acting on a proteintransferase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingcatalytic activcatalytic activity, acting on a proteintransferase acttransferase activityprotein bindingprotein bindingion bindingion bindingcarbohydrate decarbohydrate derivative bindingorganic cyclic organic cyclic compound bindingheterocyclic coheterocyclic compound bindingsmall molecule small molecule bindingdrug bindingdrug binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IDA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0009755 hormone-mediated signaling pathway IDA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035329 hippo signaling TAS
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0043065 positive regulation of apoptotic process IBA
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity IDA
 biological_processGO:0046620 regulation of organ growth IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IMP
 cellular_componentGO:0000922 spindle pole IDA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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