27161


Homo sapiens (NCBI)

Features
Gene ID: 27161
  
Biological name :
  
Synonyms : AGO2 / argonaute 2, RISC catalytic component / CASC7|EIF2C2|LINC00980|PPD|Q10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 225827_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016868806.1
RefSeq - 1034659935
RefSeq - 257467482
RefSeq - 29171734
RefSeq - 767952820
RefSeq - 767952822
RefSeq - NC_000008.11
RefSeq - NP_001158095.1
RefSeq - NP_036286.2
RefSeq - XP_011515267.1
RefSeq - XP_011515268.1
RefSeq - XP_011515270.2
RefSeq - 1034659931
RefSeq - NM_001164623.2
RefSeq - NM_012154.4
RefSeq - XM_011516968.2
RefSeq - XM_017013317.2
RefSeq - XM_011516965.2
RefSeq - XM_011516966.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000123908 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006412 translation NAS
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0007223 Wnt signaling pathway, calcium modulating pathway TAS
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010501 RNA secondary structure unwinding IMP
 biological_processGO:0010586 miRNA metabolic process TAS
 biological_processGO:0030422 production of siRNA involved in RNA interference TAS
 biological_processGO:0031047 gene silencing by RNA ISS
 biological_processGO:0031054 pre-miRNA processing IDA
 biological_processGO:0035087 siRNA loading onto RISC involved in RNA interference IDA
 biological_processGO:0035194 posttranscriptional gene silencing by RNA TAS
 biological_processGO:0035196 production of miRNAs involved in gene silencing by miRNA IDA
 biological_processGO:0035278 miRNA mediated inhibition of translation IMP
 biological_processGO:0035279 mRNA cleavage involved in gene silencing by miRNA IMP
 biological_processGO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA IDA
 biological_processGO:0045766 positive regulation of angiogenesis IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0045947 negative regulation of translational initiation IDA
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening ISS
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 biological_processGO:0090625 mRNA cleavage involved in gene silencing by siRNA IMP
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ISS
 biological_processGO:1901165 positive regulation of trophoblast cell migration IMP
 biological_processGO:1905618 positive regulation of miRNA mediated inhibition of translation IDA
 cellular_componentGO:0000932 P-body IDA
 cellular_componentGO:0005634 nucleus IC
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005844 polysome IDA
 cellular_componentGO:0005845 mRNA cap binding complex IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016442 RISC complex IDA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0035068 micro-ribonucleoprotein complex IDA
 cellular_componentGO:0070062 extracellular exosome IDA
 cellular_componentGO:0070578 RISC-loading complex IDA
 cellular_componentGO:1990904 ribonucleoprotein complex IDA
 molecular_functionGO:0000340 RNA 7-methylguanosine cap binding IDA
 molecular_functionGO:0000993 RNA polymerase II core binding IDA
 molecular_functionGO:0001047 core promoter binding IMP
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0003727 single-stranded RNA binding IDA
 molecular_functionGO:0003743 translation initiation factor activity NAS
 molecular_functionGO:0004521 endoribonuclease activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0035197 siRNA binding IDA
 molecular_functionGO:0035198 miRNA binding TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA IDA
 molecular_functionGO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA IMP
 molecular_functionGO:0098808 mRNA cap binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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