29108


Homo sapiens (NCBI)

Features
Gene ID: 29108
  
Biological name :
  
Synonyms : ASC|CARD5|TMS|TMS-1|TMS1 / PYCARD / PYD and CARD domain containing
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 221666_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 10835256
RefSeq - 22035620
RefSeq - NC_000016.10
RefSeq - NG_029446.1
RefSeq - NP_037390.2
RefSeq - NP_660183.1
RefSeq - NM_145183.1
RefSeq - NM_013258.4
RefSeq - NM_145182.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000103490 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001773 myeloid dendritic cell activation IMP
 biological_processGO:0002218 activation of innate immune response IDA
 biological_processGO:0002277 myeloid dendritic cell activation involved in immune response ISS
 biological_processGO:0002588 positive regulation of antigen processing and presentation of peptide antigen via MHC class II ISS
 biological_processGO:0002821 positive regulation of adaptive immune response IMP
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process NAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:0030838 positive regulation of actin filament polymerization ISS
 biological_processGO:0031647 regulation of protein stability ISS
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0032688 negative regulation of interferon-beta production IMP
 biological_processGO:0032729 positive regulation of interferon-gamma production ISS
 biological_processGO:0032755 positive regulation of interleukin-6 production ISS
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IMP
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IDA
 biological_processGO:0042104 positive regulation of activated T cell proliferation ISS
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0044351 macropinocytosis ISS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IDA
 biological_processGO:0050766 positive regulation of phagocytosis ISS
 biological_processGO:0050829 defense response to Gram-negative bacterium IMP
 biological_processGO:0050870 positive regulation of T cell activation IMP
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IPI
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:0071347 cellular response to interleukin-1 IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IDA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IMP
 biological_processGO:0090197 positive regulation of chemokine secretion IMP
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IDA
 biological_processGO:2000406 positive regulation of T cell migration ISS
 biological_processGO:2000484 positive regulation of interleukin-8 secretion IMP
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IMP
 biological_processGO:2001056 positive regulation of cysteine-type endopeptidase activity IDA
 biological_processGO:2001181 positive regulation of interleukin-10 secretion IMP
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IDA
 biological_processGO:2001242 regulation of intrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008385 IkappaB kinase complex TAS
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0072558 NLRP1 inflammasome complex IDA
 cellular_componentGO:0072559 NLRP3 inflammasome complex IDA
 cellular_componentGO:0097169 AIM2 inflammasome complex IDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0005138 interleukin-6 receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005523 tropomyosin binding IPI
 molecular_functionGO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process NAS
 molecular_functionGO:0017024 myosin I binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0032090 Pyrin domain binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0070700 BMP receptor binding IPI
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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