3084


Homo sapiens (NCBI)

Features
Gene ID: 3084
  
Biological name :
  
Synonyms : ARIA|GGF|GGF2|HGL|HRG|HRG1|HRGA|MST131|MSTP131|NDF|NRG1-IT2|SMDF / neuregulin 1 / NRG1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206237_s_at (Human Genome U133 Plus 2.0 Array)   206343_s_at (Human Genome U133 Plus 2.0 Array)   208230_s_at (Human Genome U133 Plus 2.0 Array)   208231_at (Human Genome U133 Plus 2.0 Array)   208232_x_at (Human Genome U133 Plus 2.0 Array)   208241_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 236463969
RefSeq - 1016080832
RefSeq - 1016081258
RefSeq - 1016081731
RefSeq - 1016081781
RefSeq - 1016081801
RefSeq - 1034660107
RefSeq - 1034660109
RefSeq - 1034660111
RefSeq - 1034660113
RefSeq - 1034660116
RefSeq - 1034660118
RefSeq - 1034660120
RefSeq - 1034660122
RefSeq - 116006955
RefSeq - 116006957
RefSeq - 116006959
RefSeq - 116006965
RefSeq - 116006967
RefSeq - 1370512283
RefSeq - 236461509
RefSeq - 236461846
RefSeq - 236462348
RefSeq - 236462773
RefSeq - 236462984
RefSeq - 236463556
RefSeq - 1015860412
RefSeq - 236464356
RefSeq - 236464528
RefSeq - 530387739
RefSeq - 530387741
RefSeq - 578815305
RefSeq - 7669518
RefSeq - 7669520
RefSeq - 7669526
RefSeq - 767950843
RefSeq - NC_000008.11
RefSeq - NG_012005.2
RefSeq - NP_001153467.1
RefSeq - NP_001153468.1
RefSeq - NP_001153471.1
RefSeq - NP_001153473.1
RefSeq - NP_001153474.1
RefSeq - NP_001153476.1
RefSeq - NP_001153477.1
RefSeq - NP_001153479.1
RefSeq - NP_001153480.1
RefSeq - NP_001309126.1
RefSeq - NP_001309130.1
RefSeq - NP_001309131.1
RefSeq - NP_001309134.1
RefSeq - NP_001309135.1
RefSeq - NP_001309136.1
RefSeq - NP_004486.2
RefSeq - NP_039250.2
RefSeq - NP_039251.2
RefSeq - NP_039252.2
RefSeq - NP_039253.1
RefSeq - NP_039254.1
RefSeq - NP_039256.2
RefSeq - NP_039258.1
RefSeq - XP_005273543.1
RefSeq - XP_005273544.1
RefSeq - XP_006716398.1
RefSeq - XP_011542814.1
RefSeq - XP_016868854.1
RefSeq - XP_016868855.1
RefSeq - XP_016868856.1
RefSeq - XP_016868857.1
RefSeq - XP_016868858.1
RefSeq - XP_016868859.1
RefSeq - XP_016868860.1
RefSeq - XP_016868861.1
RefSeq - XP_024302911.1
RefSeq - NM_001159995.2
RefSeq - NM_001159996.2
RefSeq - NM_001159999.2
RefSeq - NM_001160001.2
RefSeq - NM_001160002.1
RefSeq - NM_001160004.2
RefSeq - NM_001160005.1
RefSeq - NM_001160007.1
RefSeq - NM_001160008.1
RefSeq - NM_001322197.1
RefSeq - NM_001322201.1
RefSeq - NM_001322202.1
RefSeq - NM_001322205.1
RefSeq - NM_001322206.1
RefSeq - NM_001322207.1
RefSeq - NM_004495.3
RefSeq - NM_013956.4
RefSeq - NM_013957.4
RefSeq - NM_013958.3
RefSeq - NM_013959.3
RefSeq - NM_013960.4
RefSeq - NM_013962.2
RefSeq - NM_013964.4
RefSeq - XM_011544512.2
RefSeq - XM_017013365.2
RefSeq - XM_017013366.2
RefSeq - XM_017013367.1
RefSeq - XM_017013368.2
RefSeq - XM_017013369.2
RefSeq - XM_017013370.1
RefSeq - XM_017013371.2
RefSeq - XM_017013372.2
RefSeq - XM_024447143.1
RefSeq - XM_005273486.3
RefSeq - XM_005273487.3
RefSeq - XM_006716335.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000157168 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001964 startle response IEA
 biological_processGO:0003161 cardiac conduction system development IEA
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis IDA
 biological_processGO:0007154 cell communication TAS
 biological_processGO:0007171 activation of transmembrane receptor protein tyrosine kinase activity IEA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0007422 peripheral nervous system development IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008366 axon ensheathment IEA
 biological_processGO:0009790 embryo development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014032 neural crest cell development TAS
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021781 glial cell fate commitment IEA
 biological_processGO:0021842 chemorepulsion involved in interneuron migration from the subpallium to the cortex IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030879 mammary gland development TAS
 biological_processGO:0031643 positive regulation of myelination IEA
 biological_processGO:0032148 activation of protein kinase B activity IMP
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0038127 ERBB signaling pathway IMP
 biological_processGO:0038128 ERBB2 signaling pathway TAS
 biological_processGO:0038129 ERBB3 signaling pathway IDA
 biological_processGO:0042060 wound healing TAS
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0043496 regulation of protein homodimerization activity TAS
 biological_processGO:0043497 regulation of protein heterodimerization activity IDA
 biological_processGO:0045213 neurotransmitter receptor metabolic process IEA
 biological_processGO:0045773 positive regulation of axon extension IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046579 positive regulation of Ras protein signal transduction IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048513 animal organ development IBA
 biological_processGO:0048663 neuron fate commitment IEA
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051048 negative regulation of secretion IDA
 biological_processGO:0051155 positive regulation of striated muscle cell differentiation ISS
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0055007 cardiac muscle cell differentiation ISS
 biological_processGO:0060379 cardiac muscle cell myoblast differentiation IDA
 biological_processGO:0060956 endocardial cell differentiation IDA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0070886 positive regulation of calcineurin-NFAT signaling cascade IEA
 biological_processGO:2000010 positive regulation of protein localization to cell surface IEA
 biological_processGO:2000145 regulation of cell motility TAS
 biological_processGO:2000727 positive regulation of cardiac muscle cell differentiation IEA
 biological_processGO:2001223 negative regulation of neuron migration IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030673 axolemma IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0044297 cell body IEA
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005125 cytokine activity TAS
 molecular_functionGO:0005176 ErbB-2 class receptor binding IEA
 molecular_functionGO:0005178 integrin binding IDA
 molecular_functionGO:0008083 growth factor activity NAS
 molecular_functionGO:0030296 protein tyrosine kinase activator activity IBA
 molecular_functionGO:0030297 transmembrane receptor protein tyrosine kinase activator activity NAS
 molecular_functionGO:0030971 receptor tyrosine kinase binding NAS
 molecular_functionGO:0043125 ErbB-3 class receptor binding IDA
 molecular_functionGO:0045499 chemorepellent activity IEA
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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