3148


Homo sapiens (NCBI)

Features
Gene ID: 3148
  
Biological name :
  
Synonyms : high mobility group box 2 / HMG2 / HMGB2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208808_s_at (Human Genome U133 Plus 2.0 Array)   236091_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 11321591
RefSeq - 194688133
RefSeq - 194688135
RefSeq - NC_000004.12
RefSeq - NP_001124160.1
RefSeq - NP_001124161.1
RefSeq - NP_002120.1
RefSeq - NM_001130688.1
RefSeq - NM_001130689.1
RefSeq - NM_002129.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000164104 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IDA
 biological_processGO:0002437 inflammatory response to antigenic stimulus ISS
 biological_processGO:0006265 DNA topological change ISS
 biological_processGO:0006309 apoptotic DNA fragmentation TAS
 biological_processGO:0006325 chromatin organization NAS
 biological_processGO:0006334 nucleosome assembly NAS
 biological_processGO:0006338 chromatin remodeling IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0007289 spermatid nucleus differentiation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0032075 positive regulation of nuclease activity IDA
 biological_processGO:0032392 DNA geometric change ISS
 biological_processGO:0032496 response to lipopolysaccharide ISS
 biological_processGO:0032728 positive regulation of interferon-beta production IEA
 biological_processGO:0033151 V(D)J recombination ISS
 biological_processGO:0042493 response to drug ISS
 biological_processGO:0043388 positive regulation of DNA binding IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response IEA
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IMP
 biological_processGO:0045654 positive regulation of megakaryocyte differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048545 response to steroid hormone IEA
 biological_processGO:0050767 regulation of neurogenesis ISS
 biological_processGO:0050829 defense response to Gram-negative bacterium IDA
 biological_processGO:0050830 defense response to Gram-positive bacterium IDA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0051103 DNA ligation involved in DNA repair ISS
 biological_processGO:0060326 cell chemotaxis IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEP
 biological_processGO:0072091 regulation of stem cell proliferation ISS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 cellular_componentGO:0000790 nuclear chromatin ISS
 cellular_componentGO:0000793 condensed chromosome IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000400 four-way junction DNA binding ISS
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding ISS
 molecular_functionGO:0003677 DNA binding IMP
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003684 damaged DNA binding IDA
 molecular_functionGO:0003690 double-stranded DNA binding ISS
 molecular_functionGO:0003697 single-stranded DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding ISS
 molecular_functionGO:0008144 drug binding ISS
 molecular_functionGO:0008301 DNA binding, bending IDA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0044378 non-sequence-specific DNA binding, bending ISS
 molecular_functionGO:0050786 RAGE receptor binding IGI
 molecular_functionGO:0097100 supercoiled DNA binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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