326


Homo sapiens (NCBI)

Features
Gene ID: 326
  
Biological name :
  
Synonyms : AIRE / AIRE1|APECED|APS1|APSI|PGA1 / autoimmune regulator
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208090_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000021.9
RefSeq - NG_009556.1
RefSeq - NP_000374.1
RefSeq - 4557291
RefSeq - NM_000383.3
RefSeq - NM_000658.2
RefSeq - NM_000659.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000160224 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002458 peripheral T cell tolerance induction ISS
 biological_processGO:0002509 central tolerance induction to self antigen IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0006959 humoral immune response IEA
 biological_processGO:0032602 chemokine production ISS
 biological_processGO:0045060 negative thymic T cell selection IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0097536 thymus epithelium morphogenesis ISS
 biological_processGO:2000410 regulation of thymocyte migration ISS
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body ISS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0045182 translation regulator activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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