3280


Homo sapiens (NCBI)

Features
Gene ID: 3280
  
Biological name :
  
Synonyms : HES1 / HES-1|HHL|HRY|bHLHb39 / hes family bHLH transcription factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203393_at (Human Genome U133 Plus 2.0 Array)   203394_s_at (Human Genome U133 Plus 2.0 Array)   203395_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 5031763
RefSeq - NC_000003.12
RefSeq - NP_005515.1
RefSeq - NM_005524.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000114315 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001756 somitogenesis IBA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0003143 embryonic heart tube morphogenesis ISS
 biological_processGO:0003151 outflow tract morphogenesis ISS
 biological_processGO:0003266 regulation of secondary heart field cardioblast proliferation IEA
 biological_processGO:0003281 ventricular septum development ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007219 Notch signaling pathway IMP
 biological_processGO:0007224 smoothened signaling pathway IEA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0021555 midbrain-hindbrain boundary morphogenesis IEA
 biological_processGO:0021557 oculomotor nerve development IEA
 biological_processGO:0021558 trochlear nerve development IEA
 biological_processGO:0021575 hindbrain morphogenesis IEA
 biological_processGO:0021861 forebrain radial glial cell differentiation ISS
 biological_processGO:0021984 adenohypophysis development IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0035910 ascending aorta morphogenesis ISS
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISS
 biological_processGO:0042668 auditory receptor cell fate determination IEA
 biological_processGO:0043388 positive regulation of DNA binding ISS
 biological_processGO:0045598 regulation of fat cell differentiation IEA
 biological_processGO:0045608 negative regulation of inner ear auditory receptor cell differentiation IEA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0045977 positive regulation of mitotic cell cycle, embryonic ISS
 biological_processGO:0046331 lateral inhibition IEA
 biological_processGO:0046425 regulation of JAK-STAT cascade ISS
 biological_processGO:0046427 positive regulation of JAK-STAT cascade ISS
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048538 thymus development ISS
 biological_processGO:0048667 cell morphogenesis involved in neuron differentiation IEA
 biological_processGO:0048711 positive regulation of astrocyte differentiation ISS
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation ISS
 biological_processGO:0048844 artery morphogenesis ISS
 biological_processGO:0050678 regulation of epithelial cell proliferation IEA
 biological_processGO:0050767 regulation of neurogenesis IBA
 biological_processGO:0060122 inner ear receptor cell stereocilium organization IEA
 biological_processGO:0060164 regulation of timing of neuron differentiation IEA
 biological_processGO:0060253 negative regulation of glial cell proliferation ISS
 biological_processGO:0060412 ventricular septum morphogenesis ISS
 biological_processGO:0060675 ureteric bud morphogenesis IEA
 biological_processGO:0060716 labyrinthine layer blood vessel development IEA
 biological_processGO:0061009 common bile duct development IEA
 biological_processGO:0061106 negative regulation of stomach neuroendocrine cell differentiation IEA
 biological_processGO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis IEA
 biological_processGO:0061626 pharyngeal arch artery morphogenesis ISS
 biological_processGO:0065003 protein-containing complex assembly ISS
 biological_processGO:0072012 glomerulus vasculature development IEA
 biological_processGO:0072049 comma-shaped body morphogenesis IEA
 biological_processGO:0072050 S-shaped body morphogenesis IEA
 biological_processGO:0072141 renal interstitial fibroblast development IEA
 biological_processGO:0072282 metanephric nephron tubule morphogenesis IEA
 biological_processGO:0090102 cochlea development IEA
 biological_processGO:0090162 establishment of epithelial cell polarity IEA
 biological_processGO:0097084 vascular smooth muscle cell development ISS
 biological_processGO:0097150 neuronal stem cell population maintenance IEP
 biological_processGO:2000227 negative regulation of pancreatic A cell differentiation IEA
 biological_processGO:2000737 negative regulation of stem cell differentiation IMP
 biological_processGO:2000974 negative regulation of pro-B cell differentiation IMP
 biological_processGO:2000978 negative regulation of forebrain neuron differentiation ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISS
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding NAS
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:0070888 E-box binding IBA
 molecular_functionGO:0071820 N-box binding ISS
 molecular_functionGO:1990837 sequence-specific double-stranded DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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