3303


Homo sapiens (NCBI)

Features
Gene ID: 3303
  
Biological name :
  
Synonyms : heat shock protein family A (Hsp70) member 1A / HEL-S-103|HSP70-1|HSP70-1A|HSP70.1|HSP70I|HSP72|HSPA1 / HSPA1A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 200799_at (Human Genome U133 Plus 2.0 Array)   200800_s_at (Human Genome U133 Plus 2.0 Array)   202581_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NT_167248.2
RefSeq - NC_000006.12
RefSeq - NG_011855.1
RefSeq - 194248072
RefSeq - NP_005336.3
RefSeq - NT_113891.3
RefSeq - NT_167244.2
RefSeq - NT_167245.2
RefSeq - NM_005345.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000204389 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006402 mRNA catabolic process IDA
 biological_processGO:0006986 response to unfolded protein IDA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010941 regulation of cell death IMP
 biological_processGO:0030308 negative regulation of cell growth IMP
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0031396 regulation of protein ubiquitination IDA
 biological_processGO:0031397 negative regulation of protein ubiquitination IDA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IMP
 biological_processGO:0033120 positive regulation of RNA splicing IDA
 biological_processGO:0034599 cellular response to oxidative stress TAS
 biological_processGO:0034605 cellular response to heat IDA
 biological_processGO:0034620 cellular response to unfolded protein IMP
 biological_processGO:0042026 protein refolding IMP
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043488 regulation of mRNA stability TAS
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IMP
 biological_processGO:0046034 ATP metabolic process IDA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050821 protein stabilization TAS
 biological_processGO:0051085 chaperone cofactor-dependent protein refolding IBA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0051131 chaperone-mediated protein complex assembly IDA
 biological_processGO:0060548 negative regulation of cell death IMP
 biological_processGO:0070370 cellular heat acclimation IMP
 biological_processGO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway IMP
 biological_processGO:0090063 positive regulation of microtubule nucleation IMP
 biological_processGO:0090084 negative regulation of inclusion body assembly IDA
 biological_processGO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress IDA
 biological_processGO:1900034 regulation of cellular response to heat TAS
 biological_processGO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IDA
 biological_processGO:1901673 regulation of mitotic spindle assembly IMP
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IDA
 biological_processGO:1902380 positive regulation of endoribonuclease activity IDA
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
 cellular_componentGO:0000151 ubiquitin ligase complex IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005814 centriole IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0016234 inclusion body IDA
 cellular_componentGO:0016235 aggresome IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0031982 vesicle HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072562 blood microparticle HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 cellular_componentGO:1990904 ribonucleoprotein complex IDA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IDA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0031249 denatured protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042623 ATPase activity, coupled TAS
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0044183 protein binding involved in protein folding IDA
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0047485 protein N-terminus binding IPI
 molecular_functionGO:0051082 unfolded protein binding TAS
 molecular_functionGO:0051787 misfolded protein binding IBA
 molecular_functionGO:0055131 C3HC4-type RING finger domain binding IPI
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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