3309


Homo sapiens (NCBI)

Features
Gene ID: 3309
  
Biological name :
  
Synonyms : BIP|GRP78|HEL-S-89n|MIF2 / heat shock protein family A (Hsp70) member 5 / HSPA5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 211936_at (Human Genome U133 Plus 2.0 Array)   230031_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 16507237
RefSeq - NC_000009.12
RefSeq - NG_027761.1
RefSeq - NP_005338.1
RefSeq - NM_005347.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000044574 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006983 ER overload response IEA
 biological_processGO:0006986 response to unfolded protein IBA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0021589 cerebellum structural organization IEA
 biological_processGO:0021680 cerebellar Purkinje cell layer development IEA
 biological_processGO:0021762 substantia nigra development HEP
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway TAS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response TAS
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0034605 cellular response to heat IBA
 biological_processGO:0034620 cellular response to unfolded protein IBA
 biological_processGO:0034975 protein folding in endoplasmic reticulum TAS
 biological_processGO:0035437 maintenance of protein localization in endoplasmic reticulum IMP
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0036499 PERK-mediated unfolded protein response TAS
 biological_processGO:0036500 ATF6-mediated unfolded protein response TAS
 biological_processGO:0042026 protein refolding IBA
 biological_processGO:0042149 cellular response to glucose starvation IDA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0051085 chaperone cofactor-dependent protein refolding IBA
 biological_processGO:0051402 neuron apoptotic process IEA
 biological_processGO:0060904 regulation of protein folding in endoplasmic reticulum TAS
 biological_processGO:0071236 cellular response to antibiotic IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:0071287 cellular response to manganese ion IEA
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:0090074 negative regulation of protein homodimerization activity TAS
 biological_processGO:0097501 stress response to metal ion IEA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1903891 regulation of ATF6-mediated unfolded protein response TAS
 biological_processGO:1903894 regulation of IRE1-mediated unfolded protein response TAS
 biological_processGO:1903895 negative regulation of IRE1-mediated unfolded protein response ISS
 biological_processGO:1903897 regulation of PERK-mediated unfolded protein response TAS
 biological_processGO:1904313 response to methamphetamine hydrochloride IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 biological_processGO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress TAS
 cellular_componentGO:0005634 nucleus IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005790 smooth endoplasmic reticulum IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0034663 endoplasmic reticulum chaperone complex IDA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity ISS
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0031072 heat shock protein binding IBA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042623 ATPase activity, coupled IBA
 molecular_functionGO:0043022 ribosome binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0051082 unfolded protein binding TAS
 molecular_functionGO:0051087 chaperone binding TAS
 molecular_functionGO:0051787 misfolded protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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