3416


Homo sapiens (NCBI)

Features
Gene ID: 3416
  
Biological name :
  
Synonyms : IDE / insulin degrading enzyme / INSULYSIN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203327_at (Human Genome U133 Plus 2.0 Array)   203328_x_at (Human Genome U133 Plus 2.0 Array)   217496_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001309725.1
RefSeq - NP_001309726.1
RefSeq - NP_004960.2
RefSeq - 1034568073
RefSeq - 155969707
RefSeq - 260099676
RefSeq - NC_000010.11
RefSeq - NG_013012.1
RefSeq - XP_016871676.1
RefSeq - XP_016871677.1
RefSeq - XP_016871678.1
RefSeq - XP_016871679.1
RefSeq - 1017029430
RefSeq - 1017029415
RefSeq - 1017029440
RefSeq - 1017029480
RefSeq - 1017029491
RefSeq - 1034568067
RefSeq - 1034568069
RefSeq - 1034568071
RefSeq - NP_001159418.1
RefSeq - NP_001309722.1
RefSeq - NP_001309723.1
RefSeq - NP_001309724.1
RefSeq - XR_945727.3
RefSeq - NM_001165946.1
RefSeq - NM_001322793.1
RefSeq - NM_001322794.1
RefSeq - NM_001322795.1
RefSeq - NM_001322796.1
RefSeq - NM_001322797.1
RefSeq - NM_004969.3
RefSeq - NR_136399.1
RefSeq - XM_017016187.1
RefSeq - XM_017016188.1
RefSeq - XM_017016189.1
RefSeq - XM_017016190.1
RefSeq - XR_001747103.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000119912 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0006625 protein targeting to peroxisome TAS
 biological_processGO:0008286 insulin receptor signaling pathway NAS
 biological_processGO:0008340 determination of adult lifespan IDA
 biological_processGO:0010815 bradykinin catabolic process IDA
 biological_processGO:0010992 ubiquitin recycling IDA
 biological_processGO:0032461 positive regulation of protein oligomerization IDA
 biological_processGO:0042447 hormone catabolic process IEA
 biological_processGO:0043171 peptide catabolic process IBA
 biological_processGO:0045732 positive regulation of protein catabolic process TAS
 biological_processGO:0045861 negative regulation of proteolysis IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050435 amyloid-beta metabolic process IDA
 biological_processGO:0051260 protein homooligomerization IDA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IDA
 biological_processGO:0097242 amyloid-beta clearance ISS
 biological_processGO:1901142 insulin metabolic process IDA
 biological_processGO:1901143 insulin catabolic process IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005777 peroxisome IDA
 cellular_componentGO:0005782 peroxisomal matrix TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0031597 cytosolic proteasome complex IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0031626 beta-endorphin binding IEA
 molecular_functionGO:0042277 peptide binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043559 insulin binding IPI
 molecular_functionGO:0140036 ubiquitin-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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