3456


Homo sapiens (NCBI)
responsecellregulationimmunesignalingactivationpathwayinvolvedbreceptoractivitytnaturalkillervirusdifferentiationcellularexogenousdsrnatypeinterferoncytokineextracellularadaptivehumoralsurfacebloodcoagulationcytokine-mediatedpeptidyl-serine

Features
Gene ID: 3456
  
Biological name :
  
Synonyms : IFB|IFF|IFN-beta|IFNB / IFNB1 / interferon beta 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 208173_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4504603
RefSeq - NC_000009.12
RefSeq - NP_002167.1
RefSeq - NM_002176.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000171855 to get all the annotations available for this gene.


Gene Ontology (GO)
immune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmune responsecell activationimmune effector processcell communicationcellular response to stimulusresponse to stressregulation of biological qualitycoagulationresponse to external stimulusresponse to biotic stimulusregulation of molecular functionresponse to chemicalanatomical structure developmentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processleukocyte proliferationinterspecies interaction between organismsbiosynthetic processcell adhesionproduction of molecular mediator of immune responsecytokine productioncell deathimmunimmune responsecell cell activationimmunimmune effector processcell cell communicationcellucellular response to stimulusresporesponse to stressregulregulation of biological qualitycoagucoagulationresporesponse to external stimulusresporesponse to biotic stimulusregulregulation of molecular functionresporesponse to chemicalanatoanatomical structure developmentcellucellular developmental processnitronitrogen compound metabolic processcellucellular metabolic processprimaprimary metabolic processorganorganic substance metabolic processleukoleukocyte proliferationinterinterspecies interaction between organismsbiosybiosynthetic processcell cell adhesionproduproduction of molecular mediator of immune responsecytokcytokine productioncell cell death
protein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingreceptor regulator activityprotein-containing complex bindingtransferase activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activityprotein-containing complex bindingprotein-containing complex bindingtransferase activitytransferase activity
extracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IBA
 biological_processGO:0002286 T cell activation involved in immune response IBA
 biological_processGO:0002312 B cell activation involved in immune response IMP
 biological_processGO:0002323 natural killer cell activation involved in immune response IBA
 biological_processGO:0006959 humoral immune response IBA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0009615 response to virus NAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0030101 natural killer cell activation NAS
 biological_processGO:0030183 B cell differentiation IBA
 biological_processGO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein IDA
 biological_processGO:0035458 cellular response to interferon-beta IDA
 biological_processGO:0042100 B cell proliferation NAS
 biological_processGO:0043330 response to exogenous dsRNA IDA
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045089 positive regulation of innate immune response NAS
 biological_processGO:0045343 regulation of MHC class I biosynthetic process NAS
 biological_processGO:0045581 negative regulation of T cell differentiation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0051607 defense response to virus TAS
 biological_processGO:0060337 type I interferon signaling pathway TAS
 biological_processGO:0071360 cellular response to exogenous dsRNA TAS
 biological_processGO:2000552 negative regulation of T-helper 2 cell cytokine production IDA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005132 type I interferon receptor binding NAS
 molecular_functionGO:0008811 chloramphenicol O-acetyltransferase activity IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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