3479


Homo sapiens (NCBI)

Features
Gene ID: 3479
  
Biological name :
  
Synonyms : IGF1 / IGF|IGF-I|IGFI|MGF / insulin like growth factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209540_at (Human Genome U133 Plus 2.0 Array)   209541_at (Human Genome U133 Plus 2.0 Array)   209542_x_at (Human Genome U133 Plus 2.0 Array)   211577_s_at (Human Genome U133 Plus 2.0 Array)   241072_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034579374
RefSeq - 1034579378
RefSeq - 1034579380
RefSeq - 1034579382
RefSeq - 11024682
RefSeq - 163659899
RefSeq - 163659901
RefSeq - 163659903
RefSeq - NC_000012.12
RefSeq - NG_011713.1
RefSeq - NP_000609.1
RefSeq - NP_001104753.1
RefSeq - NP_001104754.1
RefSeq - NP_001104755.1
RefSeq - XP_016874748.1
RefSeq - XP_016874750.1
RefSeq - XP_016874751.1
RefSeq - XP_016874752.1
RefSeq - NM_000618.4
RefSeq - NM_001111283.2
RefSeq - NM_001111284.1
RefSeq - NM_001111285.2
RefSeq - XM_017019259.1
RefSeq - XM_017019261.1
RefSeq - XM_017019262.2
RefSeq - XM_017019263.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000017427 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IMP
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0001775 cell activation IDA
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007265 Ras protein signal transduction TAS
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0009408 response to heat IDA
 biological_processGO:0009441 glycolate metabolic process TAS
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010560 positive regulation of glycoprotein biosynthetic process IMP
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IMP
 biological_processGO:0010628 positive regulation of gene expression IGI
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IMP
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration IDA
 biological_processGO:0014896 muscle hypertrophy IMP
 biological_processGO:0014904 myotube cell development IDA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IDA
 biological_processGO:0030166 proteoglycan biosynthetic process IMP
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0032148 activation of protein kinase B activity IMP
 biological_processGO:0033160 positive regulation of protein import into nucleus, translocation IDA
 biological_processGO:0034392 negative regulation of smooth muscle cell apoptotic process IDA
 biological_processGO:0035630 bone mineralization involved in bone maturation IDA
 biological_processGO:0040014 regulation of multicellular organism growth IEP
 biological_processGO:0042104 positive regulation of activated T cell proliferation IDA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043388 positive regulation of DNA binding IDA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043491 protein kinase B signaling IMP
 biological_processGO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway IDA
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045445 myoblast differentiation IDA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IDA
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process IDA
 biological_processGO:0045821 positive regulation of glycolytic process IDA
 biological_processGO:0045840 positive regulation of mitotic nuclear division IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046326 positive regulation of glucose import IDA
 biological_processGO:0046579 positive regulation of Ras protein signal transduction IDA
 biological_processGO:0048009 insulin-like growth factor receptor signaling pathway IMP
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IDA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IDA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IDA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IDA
 biological_processGO:0050714 positive regulation of protein secretion IMP
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0051450 myoblast proliferation IDA
 biological_processGO:0060283 negative regulation of oocyte development IMP
 biological_processGO:0061051 positive regulation of cell growth involved in cardiac muscle cell development IGI
 biological_processGO:0070371 ERK1 and ERK2 cascade IMP
 biological_processGO:0070886 positive regulation of calcineurin-NFAT signaling cascade IDA
 biological_processGO:0090201 negative regulation of release of cytochrome c from mitochondria ISS
 biological_processGO:1904075 positive regulation of trophectodermal cell proliferation IMP
 biological_processGO:1904646 cellular response to amyloid-beta IGI
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IMP
 biological_processGO:1905460 negative regulation of vascular associated smooth muscle cell apoptotic process IMP
 biological_processGO:2000679 positive regulation of transcription regulatory region DNA binding IDA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0016942 insulin-like growth factor binding protein complex IC
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex IDA
 cellular_componentGO:0042567 insulin-like growth factor ternary complex IDA
 cellular_componentGO:0070382 exocytic vesicle ISS
 molecular_functionGO:0005158 insulin receptor binding IPI
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IPI
 molecular_functionGO:0005178 integrin binding IDA
 molecular_functionGO:0005179 hormone activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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