348654


Homo sapiens (NCBI)

Features
Gene ID: 348654
  
Biological name :
  
Synonyms : Gen / GEN1 / GEN1, Holliday junction 5 flap endonuclease
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1557267_s_at (Human Genome U133 Plus 2.0 Array)   228286_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_011531124.1
RefSeq - 1015809816
RefSeq - 530367045
RefSeq - 578802871
RefSeq - 767914458
RefSeq - 767914460
RefSeq - 767914463
RefSeq - NC_000002.12
RefSeq - NG_051292.1
RefSeq - NP_001123481.2
RefSeq - NP_872431.4
RefSeq - XP_005262670.1
RefSeq - XP_006712068.1
RefSeq - XP_011531122.1
RefSeq - XP_011531123.1
RefSeq - 1015809814
RefSeq - NM_001130009.2
RefSeq - NM_182625.4
RefSeq - XM_011532821.2
RefSeq - XM_011532822.2
RefSeq - XM_005262613.4
RefSeq - XM_006712005.3
RefSeq - XM_011532820.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000178295 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0000737 DNA catabolic process, endonucleolytic IBA
 biological_processGO:0000738 DNA catabolic process, exonucleolytic IBA
 biological_processGO:0010824 regulation of centrosome duplication IMP
 biological_processGO:0031297 replication fork processing IDA
 biological_processGO:0070914 UV-damage excision repair IBA
 biological_processGO:0071139 resolution of recombination intermediates IMP
 biological_processGO:0071140 resolution of mitotic recombination intermediates IMP
 biological_processGO:0072422 signal transduction involved in DNA damage checkpoint IBA
 biological_processGO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint IMP
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005813 centrosome IDA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0000400 four-way junction DNA binding IDA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004520 endodeoxyribonuclease activity TAS
 molecular_functionGO:0008310 single-stranded DNA 3"-5" exodeoxyribonuclease activity IBA
 molecular_functionGO:0008311 double-stranded DNA 3"-5" exodeoxyribonuclease activity IBA
 molecular_functionGO:0008821 crossover junction endodeoxyribonuclease activity IMP
 molecular_functionGO:0017108 5"-flap endonuclease activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0045145 single-stranded DNA 5"-3" exodeoxyribonuclease activity IBA
 molecular_functionGO:0048256 flap endonuclease activity IBA
 molecular_functionGO:0051908 double-stranded DNA 5"-3" exodeoxyribonuclease activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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