Manteia

3553

Homo sapiens (NCBI)

Features

Gene ID:	3553

Biological name :

Synonyms :	IL1B / IL-1\|IL1-BETA\|IL1F2 / interleukin 1 beta

Possible biological names infered from orthology :

Species:	Homo sapiens (NCBI)

Chr. number:
Strand:
Band:
Gene start:
Gene end:

Corresponding Affymetrix probe sets:	205067_at (Human Genome U133 Plus 2.0 Array) 39402_at (Human Genome U133 Plus 2.0 Array)

Cross references:	RefSeq - 1034613651 RefSeq - 10835145 RefSeq - NC_000002.12 RefSeq - NG_008851.1 RefSeq - NP_000567.1 RefSeq - XP_016859477.1 RefSeq - NM_000576.2 RefSeq - XM_017003988.2

See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000125538 to get all the annotations available for this gene.

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA
biological_process	GO:0000165	MAPK cascade	IMP
biological_process	GO:0000187	activation of MAPK activity	IDA
biological_process	GO:0001660	fever generation	IBA
biological_process	GO:0001666	response to hypoxia	IBA
biological_process	GO:0001934	positive regulation of protein phosphorylation	NAS
biological_process	GO:0002437	inflammatory response to antigenic stimulus	IBA
biological_process	GO:0002439	chronic inflammatory response to antigenic stimulus	IBA
biological_process	GO:0002711	positive regulation of T cell mediated immunity	IC
biological_process	GO:0006915	apoptotic process	TAS
biological_process	GO:0006954	inflammatory response	NAS
biological_process	GO:0006955	immune response	IEA
biological_process	GO:0007165	signal transduction	TAS
biological_process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IBA
biological_process	GO:0007267	cell-cell signaling	TAS
biological_process	GO:0007566	embryo implantation	TAS
biological_process	GO:0007613	memory	IBA
biological_process	GO:0008284	positive regulation of cell proliferation	IDA
biological_process	GO:0008285	negative regulation of cell proliferation	IDA
biological_process	GO:0009408	response to heat	IBA
biological_process	GO:0009743	response to carbohydrate	IEA
biological_process	GO:0010193	response to ozone	IBA
biological_process	GO:0010332	response to gamma radiation	IBA
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0010575	positive regulation of vascular endothelial growth factor production	ISS
biological_process	GO:0010628	positive regulation of gene expression	IDA
biological_process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IDA
biological_process	GO:0010829	negative regulation of glucose transmembrane transport	ISS
biological_process	GO:0014050	negative regulation of glutamate secretion	IBA
biological_process	GO:0014070	response to organic cyclic compound	IBA
biological_process	GO:0014805	smooth muscle adaptation	NAS
biological_process	GO:0019221	cytokine-mediated signaling pathway	TAS
biological_process	GO:0030213	hyaluronan biosynthetic process	IDA
biological_process	GO:0030335	positive regulation of cell migration	IDA
biological_process	GO:0030593	neutrophil chemotaxis	IEA
biological_process	GO:0030728	ovulation	IBA
biological_process	GO:0030730	sequestering of triglyceride	IDA
biological_process	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	IC
biological_process	GO:0031622	positive regulation of fever generation	ISS
biological_process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IDA
biological_process	GO:0032308	positive regulation of prostaglandin secretion	ISS
biological_process	GO:0032355	response to estradiol	IBA
biological_process	GO:0032611	interleukin-1 beta production	IEA
biological_process	GO:0032635	interleukin-6 production	IEA
biological_process	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	IDA
biological_process	GO:0032729	positive regulation of interferon-gamma production	IDA
biological_process	GO:0032755	positive regulation of interleukin-6 production	TAS
biological_process	GO:0032757	positive regulation of interleukin-8 production	IDA
biological_process	GO:0033092	positive regulation of immature T cell proliferation in thymus	IBA
biological_process	GO:0033129	positive regulation of histone phosphorylation	NAS
biological_process	GO:0033198	response to ATP	IEA
biological_process	GO:0033280	response to vitamin D	IBA
biological_process	GO:0033591	response to L-ascorbic acid	IBA
biological_process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	NAS
biological_process	GO:0035066	positive regulation of histone acetylation	NAS
biological_process	GO:0035176	social behavior	IBA
biological_process	GO:0035234	ectopic germ cell programmed cell death	IEA
biological_process	GO:0035505	positive regulation of myosin light chain kinase activity	IDA
biological_process	GO:0035634	response to stilbenoid	IBA
biological_process	GO:0035690	cellular response to drug	IDA
biological_process	GO:0035902	response to immobilization stress	IBA
biological_process	GO:0042060	wound healing	IBA
biological_process	GO:0042102	positive regulation of T cell proliferation	IDA
biological_process	GO:0042493	response to drug	IBA
biological_process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	IDA
biological_process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IEA
biological_process	GO:0043278	response to morphine	IBA
biological_process	GO:0043407	negative regulation of MAP kinase activity	ISS
biological_process	GO:0043434	response to peptide hormone	IBA
biological_process	GO:0043491	protein kinase B signaling	IMP
biological_process	GO:0043507	positive regulation of JUN kinase activity	IBA
biological_process	GO:0043525	positive regulation of neuron apoptotic process	IBA
biological_process	GO:0045080	positive regulation of chemokine biosynthetic process	IEA
biological_process	GO:0045086	positive regulation of interleukin-2 biosynthetic process	IMP
biological_process	GO:0045410	positive regulation of interleukin-6 biosynthetic process	IEA
biological_process	GO:0045429	positive regulation of nitric oxide biosynthetic process	IDA
biological_process	GO:0045471	response to ethanol	IBA
biological_process	GO:0045665	negative regulation of neuron differentiation	IBA
biological_process	GO:0045687	positive regulation of glial cell differentiation	IBA
biological_process	GO:0045766	positive regulation of angiogenesis	ISS
biological_process	GO:0045833	negative regulation of lipid metabolic process	ISS
biological_process	GO:0045840	positive regulation of mitotic nuclear division	IMP
biological_process	GO:0045893	positive regulation of transcription, DNA-templated	IDA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0046330	positive regulation of JNK cascade	ISS
biological_process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISS
biological_process	GO:0046827	positive regulation of protein export from nucleus	NAS
biological_process	GO:0048711	positive regulation of astrocyte differentiation	IBA
biological_process	GO:0050691	regulation of defense response to virus by host	IEA
biological_process	GO:0050766	positive regulation of phagocytosis	IMP
biological_process	GO:0050796	regulation of insulin secretion	IDA
biological_process	GO:0050805	negative regulation of synaptic transmission	ISS
biological_process	GO:0050995	negative regulation of lipid catabolic process	IDA
biological_process	GO:0050996	positive regulation of lipid catabolic process	ISS
biological_process	GO:0050999	regulation of nitric-oxide synthase activity	IDA
biological_process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	IDA
biological_process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA
biological_process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IDA
biological_process	GO:0051384	response to glucocorticoid	IBA
biological_process	GO:0051781	positive regulation of cell division	IEA
biological_process	GO:0060355	positive regulation of cell adhesion molecule production	NAS
biological_process	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	IDA
biological_process	GO:0070164	negative regulation of adiponectin secretion	ISS
biological_process	GO:0070372	regulation of ERK1 and ERK2 cascade	IDA
biological_process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IBA
biological_process	GO:0070487	monocyte aggregation	IDA
biological_process	GO:0070498	interleukin-1-mediated signaling pathway	TAS
biological_process	GO:0071222	cellular response to lipopolysaccharide	IBA
biological_process	GO:0071236	cellular response to antibiotic	IBA
biological_process	GO:0071260	cellular response to mechanical stimulus	IEP
biological_process	GO:0071310	cellular response to organic substance	IDA
biological_process	GO:0071333	cellular response to glucose stimulus	IBA
biological_process	GO:0071398	cellular response to fatty acid	IBA
biological_process	GO:0071407	cellular response to organic cyclic compound	IDA
biological_process	GO:0071548	response to dexamethasone	IBA
biological_process	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	IDA
biological_process	GO:0090023	positive regulation of neutrophil chemotaxis	IBA
biological_process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	IEA
biological_process	GO:1900745	positive regulation of p38MAPK cascade	ISS
biological_process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	IDA
biological_process	GO:1903140	regulation of establishment of endothelial barrier	IDA
biological_process	GO:2000173	negative regulation of branching morphogenesis of a nerve	IBA
biological_process	GO:2000178	negative regulation of neural precursor cell proliferation	IBA
biological_process	GO:2000556	positive regulation of T-helper 1 cell cytokine production	IDA
biological_process	GO:2000778	positive regulation of interleukin-6 secretion	IEA
biological_process	GO:2000866	positive regulation of estradiol secretion	IBA
biological_process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IDA
cellular_component	GO:0005576	extracellular region	TAS
cellular_component	GO:0005615	extracellular space	IMP
cellular_component	GO:0005764	lysosome	IEA
cellular_component	GO:0005829	cytosol	TAS
cellular_component	GO:0030141	secretory granule	IEA
cellular_component	GO:0070062	extracellular exosome	IEA
molecular_function	GO:0005125	cytokine activity	IMP
molecular_function	GO:0005149	interleukin-1 receptor binding	NAS
molecular_function	GO:0005178	integrin binding	IDA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0019904	protein domain specific binding	IPI

Pathways (from Reactome)

Pathway description

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr