3558


Homo sapiens (NCBI)

Features
Gene ID: 3558
  
Biological name :
  
Synonyms : IL2 / IL-2|TCGF|lymphokine / interleukin 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207849_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034639791
RefSeq - 28178861
RefSeq - NC_000004.12
RefSeq - NG_016779.1
RefSeq - NP_000577.2
RefSeq - XP_016863666.1
RefSeq - NM_000586.3
RefSeq - XM_017008177.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000109471 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002366 leukocyte activation involved in immune response IDA
 biological_processGO:0002903 negative regulation of B cell apoptotic process IDA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030101 natural killer cell activation TAS
 biological_processGO:0030217 T cell differentiation TAS
 biological_processGO:0030307 positive regulation of cell growth TAS
 biological_processGO:0030890 positive regulation of B cell proliferation IDA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032740 positive regulation of interleukin-17 production IDA
 biological_processGO:0034105 positive regulation of tissue remodeling IC
 biological_processGO:0038110 interleukin-2-mediated signaling pathway TAS
 biological_processGO:0042104 positive regulation of activated T cell proliferation IDA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045589 regulation of regulatory T cell differentiation TAS
 biological_processGO:0045591 positive regulation of regulatory T cell differentiation IEA
 biological_processGO:0045822 negative regulation of heart contraction IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046013 regulation of T cell homeostatic proliferation IEA
 biological_processGO:0048304 positive regulation of isotype switching to IgG isotypes IEA
 biological_processGO:0050672 negative regulation of lymphocyte proliferation IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050729 positive regulation of inflammatory response IC
 biological_processGO:0051024 positive regulation of immunoglobulin secretion IEA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IEA
 biological_processGO:2000320 negative regulation of T-helper 17 cell differentiation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005134 interleukin-2 receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity TAS
 molecular_functionGO:0019209 kinase activator activity TAS
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0031851 kappa-type opioid receptor binding IEA
 molecular_functionGO:0043208 glycosphingolipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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