3570


Homo sapiens (NCBI)

Features
Gene ID: 3570
  
Biological name :
  
Synonyms : CD126|IL-6R-1|IL-6RA|IL6Q|IL6RA|IL6RQ|gp80 / IL6R / interleukin 6 receptor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205945_at (Human Genome U133 Plus 2.0 Array)   217489_s_at (Human Genome U133 Plus 2.0 Array)   226333_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016856690.1
RefSeq - 1034558277
RefSeq - 1034558280
RefSeq - 31317249
RefSeq - 332309226
RefSeq - 4504673
RefSeq - 530364664
RefSeq - 530364666
RefSeq - 578800882
RefSeq - 578800884
RefSeq - NC_000001.11
RefSeq - NG_012087.1
RefSeq - NP_000556.1
RefSeq - NP_001193795.1
RefSeq - NP_852004.1
RefSeq - XP_005245196.1
RefSeq - XP_005245197.1
RefSeq - XP_006711361.1
RefSeq - XP_006711362.1
RefSeq - XP_016856688.1
RefSeq - XP_016856689.1
RefSeq - 1034558275
RefSeq - NM_000565.3
RefSeq - NM_001206866.1
RefSeq - NM_181359.2
RefSeq - XM_017001199.2
RefSeq - XM_017001200.2
RefSeq - XM_017001201.2
RefSeq - XM_005245139.2
RefSeq - XM_005245140.3
RefSeq - XM_006711298.2
RefSeq - XM_006711299.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000160712 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002384 hepatic immune response TAS
 biological_processGO:0002548 monocyte chemotaxis IC
 biological_processGO:0002690 positive regulation of leukocyte chemotaxis TAS
 biological_processGO:0002827 positive regulation of T-helper 1 type immune response IBA
 biological_processGO:0006953 acute-phase response TAS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010536 positive regulation of activation of Janus kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0032722 positive regulation of chemokine production IDA
 biological_processGO:0032729 positive regulation of interferon-gamma production IBA
 biological_processGO:0032755 positive regulation of interleukin-6 production IDA
 biological_processGO:0032816 positive regulation of natural killer cell activation IBA
 biological_processGO:0034097 response to cytokine IDA
 biological_processGO:0042104 positive regulation of activated T cell proliferation IBA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0045669 positive regulation of osteoblast differentiation TAS
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IDA
 biological_processGO:0050671 positive regulation of lymphocyte proliferation IBA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050829 defense response to Gram-negative bacterium TAS
 biological_processGO:0051135 positive regulation of NK T cell activation IBA
 biological_processGO:0070102 interleukin-6-mediated signaling pathway TAS
 biological_processGO:0070120 ciliary neurotrophic factor-mediated signaling pathway IMP
 biological_processGO:0097191 extrinsic apoptotic signaling pathway TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005896 interleukin-6 receptor complex IDA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0043514 interleukin-12 complex IBA
 cellular_componentGO:0070110 ciliary neurotrophic factor receptor complex IDA
 cellular_componentGO:0070743 interleukin-23 complex IBA
 molecular_functionGO:0004896 cytokine receptor activity IBA
 molecular_functionGO:0004897 ciliary neurotrophic factor receptor activity IMP
 molecular_functionGO:0004915 interleukin-6 receptor activity IDA
 molecular_functionGO:0005138 interleukin-6 receptor binding IPI
 molecular_functionGO:0005143 interleukin-12 receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity IBA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019955 cytokine binding IBA
 molecular_functionGO:0019981 interleukin-6 binding IPI
 molecular_functionGO:0042164 interleukin-12 alpha subunit binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0045519 interleukin-23 receptor binding IBA
 molecular_functionGO:0070119 ciliary neurotrophic factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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