3630


Homo sapiens (NCBI)

Features
Gene ID: 3630
  
Biological name :
  
Synonyms : IDDM|IDDM1|IDDM2|ILPR|IRDN|MODY10 / INS / insulin
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206598_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 297374821
RefSeq - 297374823
RefSeq - 4557671
RefSeq - 631226408
RefSeq - NC_000011.10
RefSeq - NG_007114.1
RefSeq - NG_050578.1
RefSeq - NP_000198.1
RefSeq - NP_001172026.1
RefSeq - NP_001172027.1
RefSeq - NP_001278826.1
RefSeq - NM_000207.2
RefSeq - NM_001185097.1
RefSeq - NM_001185098.1
RefSeq - NM_001291897.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000254647 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IDA
 biological_processGO:0002674 negative regulation of acute inflammatory response IDA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006521 regulation of cellular amino acid metabolic process IMP
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006953 acute-phase response IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007267 cell-cell signaling IC
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IGI
 biological_processGO:0010750 positive regulation of nitric oxide mediated signal transduction IMP
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0022898 regulation of transmembrane transporter activity IDA
 biological_processGO:0030307 positive regulation of cell growth NAS
 biological_processGO:0030335 positive regulation of cell migration ISS
 biological_processGO:0031954 positive regulation of protein autophosphorylation ISS
 biological_processGO:0032148 activation of protein kinase B activity IDA
 biological_processGO:0032270 positive regulation of cellular protein metabolic process IMP
 biological_processGO:0032460 negative regulation of protein oligomerization IDA
 biological_processGO:0032880 regulation of protein localization IDA
 biological_processGO:0033861 negative regulation of NAD(P)H oxidase activity IDA
 biological_processGO:0042060 wound healing IDA
 biological_processGO:0042177 negative regulation of protein catabolic process IDA
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045597 positive regulation of cell differentiation NAS
 biological_processGO:0045721 negative regulation of gluconeogenesis NAS
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process IDA
 biological_processGO:0045818 negative regulation of glycogen catabolic process IMP
 biological_processGO:0045821 positive regulation of glycolytic process IMP
 biological_processGO:0045840 positive regulation of mitotic nuclear division IDA
 biological_processGO:0045861 negative regulation of proteolysis IMP
 biological_processGO:0045922 negative regulation of fatty acid metabolic process IMP
 biological_processGO:0046326 positive regulation of glucose import IDA
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway IDA
 biological_processGO:0046631 alpha-beta T cell activation IDA
 biological_processGO:0046889 positive regulation of lipid biosynthetic process NAS
 biological_processGO:0048167 regulation of synaptic plasticity TAS
 biological_processGO:0050708 regulation of protein secretion IDA
 biological_processGO:0050709 negative regulation of protein secretion IDA
 biological_processGO:0050715 positive regulation of cytokine secretion IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050890 cognition TAS
 biological_processGO:0050995 negative regulation of lipid catabolic process NAS
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity NAS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0055089 fatty acid homeostasis IMP
 biological_processGO:0060266 negative regulation of respiratory burst involved in inflammatory response IDA
 biological_processGO:0060267 positive regulation of respiratory burst IDA
 biological_processGO:0090277 positive regulation of peptide hormone secretion TAS
 biological_processGO:0090336 positive regulation of brown fat cell differentiation TAS
 biological_processGO:0097755 positive regulation of blood vessel diameter NAS
 biological_processGO:0097756 negative regulation of blood vessel diameter NAS
 biological_processGO:1900182 positive regulation of protein localization to nucleus IDA
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation TAS
 biological_processGO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway NAS
 biological_processGO:1902952 positive regulation of dendritic spine maintenance IGI
 biological_processGO:1903076 regulation of protein localization to plasma membrane IGI
 biological_processGO:1903427 negative regulation of reactive oxygen species biosynthetic process IGI
 biological_processGO:1990535 neuron projection maintenance IGI
 biological_processGO:2000252 negative regulation of feeding behavior IDA
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0031904 endosome lumen TAS
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane TAS
 cellular_componentGO:0034774 secretory granule lumen TAS
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0005158 insulin receptor binding IPI
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IPI
 molecular_functionGO:0005179 hormone activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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