3645


Homo sapiens (NCBI)

Features
Gene ID: 3645
  
Biological name :
  
Synonyms : INSRR / insulin receptor related receptor / IRR
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 215776_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 31657140
RefSeq - NC_000001.11
RefSeq - NG_007493.1
RefSeq - NP_055030.1
RefSeq - NM_014215.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000027644 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IBA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway NAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030238 male sex determination IEA
 biological_processGO:0031532 actin cytoskeleton reorganization IDA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0042593 glucose homeostasis IBA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0046777 protein autophosphorylation IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071469 cellular response to alkaline pH IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0005899 insulin receptor complex IBA
 cellular_componentGO:0030424 axon IBA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity NAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005009 insulin-activated receptor activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IEA
 molecular_functionGO:0043560 insulin receptor substrate binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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