3654


Homo sapiens (NCBI)

Features
Gene ID: 3654
  
Biological name :
  
Synonyms : interleukin 1 receptor associated kinase 1 / IRAK1 / IRAK|pelle
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555784_s_at (Human Genome U133 Plus 2.0 Array)   201587_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 530422770
RefSeq - 68800243
RefSeq - 68800343
RefSeq - 68800350
RefSeq - NC_000023.11
RefSeq - NG_008387.1
RefSeq - NP_001020413.1
RefSeq - NP_001020414.1
RefSeq - NP_001560.2
RefSeq - XP_005274725.1
RefSeq - NM_001025242.1
RefSeq - NM_001025243.1
RefSeq - NM_001569.3
RefSeq - XM_005274668.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000184216 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0001959 regulation of cytokine-mediated signaling pathway IMP
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway NAS
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity IDA
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0032481 positive regulation of type I interferon production IMP
 biological_processGO:0032496 response to lipopolysaccharide IMP
 biological_processGO:0034134 toll-like receptor 2 signaling pathway IMP
 biological_processGO:0034142 toll-like receptor 4 signaling pathway IBA
 biological_processGO:0034162 toll-like receptor 9 signaling pathway TAS
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling TAS
 biological_processGO:0043406 positive regulation of MAP kinase activity IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0046777 protein autophosphorylation NAS
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
 biological_processGO:0051259 protein complex oligomerization IMP
 biological_processGO:0060337 type I interferon signaling pathway IMP
 biological_processGO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS
 biological_processGO:0070498 interleukin-1-mediated signaling pathway TAS
 biological_processGO:0070555 response to interleukin-1 IMP
 biological_processGO:0071456 cellular response to hypoxia IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005811 lipid droplet ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0045323 interleukin-1 receptor complex NAS
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004704 NF-kappaB-inducing kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IDA
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity NAS
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr