3685


Homo sapiens (NCBI)

Features
Gene ID: 3685
  
Biological name :
  
Synonyms : CD51|MSK8|VNRA|VTNR / integrin subunit alpha V / ITGAV
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202351_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 223468595
RefSeq - 223468597
RefSeq - 4504763
RefSeq - NC_000002.12
RefSeq - NP_001138471.1
RefSeq - NP_001138472.1
RefSeq - NP_002201.1
RefSeq - NM_001144999.2
RefSeq - NM_001145000.2
RefSeq - NM_002210.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000138448 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEP
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
 biological_processGO:0007155 cell adhesion IDA
 biological_processGO:0007160 cell-matrix adhesion NAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007229 integrin-mediated signaling pathway NAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010745 negative regulation of macrophage derived foam cell differentiation IMP
 biological_processGO:0010888 negative regulation of lipid storage IMP
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031589 cell-substrate adhesion IMP
 biological_processGO:0032369 negative regulation of lipid transport IMP
 biological_processGO:0033627 cell adhesion mediated by integrin IDA
 biological_processGO:0033690 positive regulation of osteoblast proliferation IEA
 biological_processGO:0034113 heterotypic cell-cell adhesion IMP
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IDA
 biological_processGO:0035987 endodermal cell differentiation IMP
 biological_processGO:0038027 apolipoprotein A-I-mediated signaling pathway IMP
 biological_processGO:0038044 transforming growth factor-beta secretion IEA
 biological_processGO:0043277 apoptotic cell clearance ISS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process IMP
 biological_processGO:0045785 positive regulation of cell adhesion IDA
 biological_processGO:0046718 viral entry into host cell TAS
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0050748 negative regulation of lipoprotein metabolic process IMP
 biological_processGO:0050764 regulation of phagocytosis IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0050919 negative chemotaxis IMP
 biological_processGO:0052066 entry of symbiont into host cell by promotion of host phagocytosis NAS
 biological_processGO:0070371 ERK1 and ERK2 cascade ISS
 biological_processGO:0070588 calcium ion transmembrane transport IDA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand ISS
 biological_processGO:2000536 negative regulation of entry of bacterium into host cell IDA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0008305 integrin complex NAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0031258 lamellipodium membrane IDA
 cellular_componentGO:0031527 filopodium membrane IDA
 cellular_componentGO:0031528 microvillus membrane IDA
 cellular_componentGO:0032587 ruffle membrane IDA
 cellular_componentGO:0034683 integrin alphav-beta3 complex IDA
 cellular_componentGO:0034684 integrin alphav-beta5 complex IDA
 cellular_componentGO:0034685 integrin alphav-beta6 complex IEA
 cellular_componentGO:0034686 integrin alphav-beta8 complex IDA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0035866 alphav-beta3 integrin-PKCalpha complex NAS
 cellular_componentGO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex IDA
 cellular_componentGO:0035868 alphav-beta3 integrin-HMGB1 complex IDA
 cellular_componentGO:0045335 phagocytic vesicle TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0001846 opsonin binding ISS
 molecular_functionGO:0001968 fibronectin binding IDA
 molecular_functionGO:0002020 protease binding IDA
 molecular_functionGO:0005080 protein kinase C binding ISS
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005245 voltage-gated calcium channel activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015026 coreceptor activity TAS
 molecular_functionGO:0017134 fibroblast growth factor binding IDA
 molecular_functionGO:0019960 C-X3-C chemokine binding IDA
 molecular_functionGO:0031994 insulin-like growth factor I binding IDA
 molecular_functionGO:0038132 neuregulin binding IDA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050431 transforming growth factor beta binding ISS
 molecular_functionGO:0050840 extracellular matrix binding IDA
 molecular_functionGO:1990430 extracellular matrix protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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