3689


Homo sapiens (NCBI)

Features
Gene ID: 3689
  
Biological name :
  
Synonyms : CD18|LAD|LCAMB|LFA-1|MAC-1|MF17|MFI7 / integrin subunit beta 2 / ITGB2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555349_a_at (Human Genome U133 Plus 2.0 Array)   202803_s_at (Human Genome U133 Plus 2.0 Array)   236988_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 578836536
RefSeq - 735367775
RefSeq - 735367803
RefSeq - 735367906
RefSeq - NC_000021.9
RefSeq - NG_007270.2
RefSeq - NP_000202.3
RefSeq - NP_001120963.2
RefSeq - NP_001290167.1
RefSeq - XP_006724064.1
RefSeq - NM_000211.4
RefSeq - NM_001127491.2
RefSeq - NM_001303238.1
RefSeq - XM_006724001.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000160255 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation NAS
 biological_processGO:0002523 leukocyte migration involved in inflammatory response IEA
 biological_processGO:0006911 phagocytosis, engulfment ISS
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0006954 inflammatory response NAS
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007159 leukocyte cell-cell adhesion IDA
 biological_processGO:0007160 cell-matrix adhesion IMP
 biological_processGO:0007229 integrin-mediated signaling pathway NAS
 biological_processGO:0007267 cell-cell signaling NAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0008360 regulation of cell shape NAS
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030101 natural killer cell activation IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030593 neutrophil chemotaxis IDA
 biological_processGO:0031623 receptor internalization ISS
 biological_processGO:0032930 positive regulation of superoxide anion generation NAS
 biological_processGO:0033627 cell adhesion mediated by integrin IBA
 biological_processGO:0034113 heterotypic cell-cell adhesion IMP
 biological_processGO:0034142 toll-like receptor 4 signaling pathway TAS
 biological_processGO:0035987 endodermal cell differentiation IEP
 biological_processGO:0043113 receptor clustering IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043315 positive regulation of neutrophil degranulation IGI
 biological_processGO:0043542 endothelial cell migration IEA
 biological_processGO:0045123 cellular extravasation IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045963 negative regulation of dopamine metabolic process NAS
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus ISS
 biological_processGO:0090314 positive regulation of protein targeting to membrane NAS
 biological_processGO:0097242 amyloid-beta clearance ISS
 biological_processGO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules NAS
 biological_processGO:1901216 positive regulation of neuron death NAS
 biological_processGO:1903980 positive regulation of microglial cell activation NAS
 biological_processGO:1990266 neutrophil migration IMP
 biological_processGO:2000363 positive regulation of prostaglandin-E synthase activity NAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion IBA
 cellular_componentGO:0008305 integrin complex NAS
 cellular_componentGO:0009897 external side of plasma membrane NAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0034687 integrin alphaL-beta2 complex IDA
 cellular_componentGO:0034688 integrin alphaM-beta2 complex NAS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0044853 plasma membrane raft IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0099568 cytoplasmic region IPI
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0001540 amyloid-beta binding ISS
 molecular_functionGO:0001851 complement component C3b binding ISS
 molecular_functionGO:0005178 integrin binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030369 ICAM-3 receptor activity IMP
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity NAS
 molecular_functionGO:0050839 cell adhesion molecule binding IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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