378478


Danio rerio (NCBI)
kinaseactivityproteinreceptorregulationmembranebindingtransmembranetyrosinephosphorylationsignalingcascadeerkintegralcomponentplasmaepidermalgrowthpathwaymulticellularorganismdevelopmentsignaltransductioncelldifferentiationapoptoticprocessmapkblood

Features
Gene ID: 378478
  
Biological name :
  
Synonyms : EGFR12|EGFR15|egfr / egfra / epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  
Possible biological names infered from orthology :
  
Species: Danio rerio (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets:
  
Cross references: RefSeq - 35903183
RefSeq - NC_007113.7
RefSeq - NP_919405.1
RefSeq - NM_194424.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSDARG00000013847 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentcellular developmental processregulation of molecular functioncell deathnitrogen componitrogen compound metabolic processcellular metabcellular metabolic processprimary metaboprimary metabolic processorganic substaorganic substance metabolic processcell communicacell communicationcellular respocellular response to stimulusanatomical stranatomical structure developmentcellular develcellular developmental processregulation of regulation of molecular functioncell deathcell death
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityion bindingcarbohydrate derivative bindingdrug bindingprotein bindinghormone bindingorganic cyclorganic cyclic compound bindingheterocyclicheterocyclic compound bindingsmall molecusmall molecule bindingcatalytic accatalytic activity, acting on a proteintransferase transferase activitysignaling resignaling receptor activityion bindingion bindingcarbohydratecarbohydrate derivative bindingdrug bindingdrug bindingprotein bindprotein bindinghormone bindhormone binding
cellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0072554 blood vessel lumenization IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009925 basal plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005006 epidermal growth factor-activated receptor activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0048408 epidermal growth factor binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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