3791


Homo sapiens (NCBI)

Features
Gene ID: 3791
  
Biological name :
  
Synonyms : CD309|FLK1|VEGFR|VEGFR2 / KDR / kinase insert domain receptor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203934_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 11321597
RefSeq - NC_000004.12
RefSeq - NG_012004.1
RefSeq - NP_002244.1
RefSeq - NM_002253.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000128052 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis TAS
 biological_processGO:0001570 vasculogenesis ISS
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis ISS
 biological_processGO:0003158 endothelium development ISS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010595 positive regulation of endothelial cell migration IMP
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016239 positive regulation of macroautophagy IGI
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035162 embryonic hemopoiesis ISS
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IMP
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IMP
 biological_processGO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway IDA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation ISS
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:0043491 protein kinase B signaling IMP
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IMP
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0050927 positive regulation of positive chemotaxis IDA
 biological_processGO:0051770 positive regulation of nitric-oxide synthase biosynthetic process IMP
 biological_processGO:0051894 positive regulation of focal adhesion assembly IDA
 biological_processGO:0051901 positive regulation of mitochondrial depolarization IGI
 biological_processGO:0070371 ERK1 and ERK2 cascade IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IMP
 biological_processGO:0090141 positive regulation of mitochondrial fission IGI
 biological_processGO:1904881 cellular response to hydrogen sulfide IDA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IDA
 biological_processGO:2001214 positive regulation of vasculogenesis ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome ISS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0030054 cell junction ISS
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0045121 membrane raft IDA
 cellular_componentGO:0097443 sorting endosome ISS
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IDA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity TAS
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IDA
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019838 growth factor binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038085 vascular endothelial growth factor binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051879 Hsp90 protein binding TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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