408


Homo sapiens (NCBI)

Features
Gene ID: 408
  
Biological name :
  
Synonyms : ARB1|ARR1 / ARRB1 / arrestin beta 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 218832_x_at (Human Genome U133 Plus 2.0 Array)   221861_at (Human Genome U133 Plus 2.0 Array)   222756_s_at (Human Genome U133 Plus 2.0 Array)   222912_at (Human Genome U133 Plus 2.0 Array)   228444_at (Human Genome U133 Plus 2.0 Array)   43511_s_at (Human Genome U133 Plus 2.0 Array)   49111_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_016873243.1
RefSeq - 1034573719
RefSeq - 1034573722
RefSeq - 1034573725
RefSeq - 1034573727
RefSeq - 10880134
RefSeq - 10880136
RefSeq - 767968186
RefSeq - 767968188
RefSeq - NC_000011.10
RefSeq - NG_028118.1
RefSeq - NP_004032.2
RefSeq - NP_064647.1
RefSeq - XP_011543336.1
RefSeq - XP_011543337.1
RefSeq - XP_016873239.1
RefSeq - XP_016873240.1
RefSeq - XP_016873241.1
RefSeq - XP_016873242.1
RefSeq - 1034573717
RefSeq - NM_004041.4
RefSeq - NM_020251.3
RefSeq - XM_017017753.1
RefSeq - XM_017017754.2
RefSeq - XM_011545034.2
RefSeq - XM_011545035.2
RefSeq - XM_017017750.1
RefSeq - XM_017017751.1
RefSeq - XM_017017752.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000137486 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0002031 G-protein coupled receptor internalization IMP
 biological_processGO:0002092 positive regulation of receptor internalization IMP
 biological_processGO:0006366 transcription by RNA polymerase II IMP
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007602 phototransduction IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016567 protein ubiquitination IMP
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0031397 negative regulation of protein ubiquitination IDA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IDA
 biological_processGO:0032717 negative regulation of interleukin-8 production IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0034393 positive regulation of smooth muscle cell apoptotic process IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IMP
 biological_processGO:0035066 positive regulation of histone acetylation IMP
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042699 follicle-stimulating hormone signaling pathway IEA
 biological_processGO:0043149 stress fiber assembly IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0090240 positive regulation of histone H4 acetylation IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005834 heterotrimeric G-protein complex TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane TAS
 cellular_componentGO:0031143 pseudopodium IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IDA
 molecular_functionGO:0004857 enzyme inhibitor activity TAS
 molecular_functionGO:0005096 GTPase activator activity IMP
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0031691 alpha-1A adrenergic receptor binding IEA
 molecular_functionGO:0031692 alpha-1B adrenergic receptor binding IEA
 molecular_functionGO:0031701 angiotensin receptor binding IPI
 molecular_functionGO:0031762 follicle-stimulating hormone receptor binding IEA
 molecular_functionGO:0031896 V2 vasopressin receptor binding IEA
 molecular_functionGO:0035612 AP-2 adaptor complex binding IEA
 molecular_functionGO:0035615 clathrin adaptor activity IEA
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IMP
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0045309 protein phosphorylated amino acid binding IEA
 molecular_functionGO:1990763 arrestin family protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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