4170


Homo sapiens (NCBI)

Features
Gene ID: 4170
  
Biological name :
  
Synonyms : BCL2L3|EAT|MCL1-ES|MCL1L|MCL1S|Mcl-1|TM|bcl2-L-3|mcl1/EAT / MCL1 / MCL1, BCL2 family apoptosis regulator
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 200796_s_at (Human Genome U133 Plus 2.0 Array)   200797_s_at (Human Genome U133 Plus 2.0 Array)   200798_x_at (Human Genome U133 Plus 2.0 Array)   214056_at (Human Genome U133 Plus 2.0 Array)   214057_at (Human Genome U133 Plus 2.0 Array)   227175_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 11386165
RefSeq - 309747067
RefSeq - 33519458
RefSeq - NC_000001.11
RefSeq - NG_029146.1
RefSeq - NP_001184249.1
RefSeq - NP_068779.1
RefSeq - NP_877495.1
RefSeq - NM_001197320.1
RefSeq - NM_021960.4
RefSeq - NM_182763.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000143384 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001709 cell fate determination NAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0008637 apoptotic mitochondrial changes IEA
 biological_processGO:0010507 negative regulation of autophagy IMP
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0019725 cellular homeostasis NAS
 biological_processGO:0034097 response to cytokine IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0071806 protein transmembrane transport IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IMP
 biological_processGO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IGI
 biological_processGO:2000811 negative regulation of anoikis IMP
 biological_processGO:2001020 regulation of response to DNA damage stimulus IMP
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0097136 Bcl-2 family protein complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008320 protein transmembrane transporter activity TAS
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0051434 BH3 domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr