4233


Homo sapiens (NCBI)

Features
Gene ID: 4233
  
Biological name :
  
Synonyms : AUTS9|DFNB97|HGFR|RCCP2|c-Met / MET / MET proto-oncogene, receptor tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203510_at (Human Genome U133 Plus 2.0 Array)   211599_x_at (Human Genome U133 Plus 2.0 Array)   213807_x_at (Human Genome U133 Plus 2.0 Array)   213816_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NP_001311330.1
RefSeq - NP_001311331.1
RefSeq - 767947837
RefSeq - NC_000007.14
RefSeq - XP_006716053.1
RefSeq - XP_011514525.1
RefSeq - 1024846616
RefSeq - NG_008996.1
RefSeq - 1024846630
RefSeq - 188595716
RefSeq - 42741655
RefSeq - 578814260
RefSeq - NP_000236.2
RefSeq - NP_001120972.1
RefSeq - XR_001744772.1
RefSeq - NM_000245.3
RefSeq - NM_001127500.2
RefSeq - NM_001324401.1
RefSeq - NM_001324402.1
RefSeq - XM_006715990.2
RefSeq - XM_011516223.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000105976 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001886 endothelial cell morphogenesis IDA
 biological_processGO:0001889 liver development IBA
 biological_processGO:0006909 phagocytosis IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway NAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010507 negative regulation of autophagy NAS
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0031116 positive regulation of microtubule polymerization IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IDA
 biological_processGO:0035635 entry of bacterium into host cell TAS
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048012 hepatocyte growth factor receptor signaling pathway IEA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IMP
 biological_processGO:0050918 positive chemotaxis IDA
 biological_processGO:0051497 negative regulation of stress fiber assembly IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling TAS
 biological_processGO:0061436 establishment of skin barrier IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0070495 negative regulation of thrombin-activated receptor signaling pathway IDA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IDA
 biological_processGO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death IMP
 biological_processGO:1905098 negative regulation of guanyl-nucleotide exchange factor activity IDA
 biological_processGO:2001028 positive regulation of endothelial cell chemotaxis IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0009986 cell surface HDA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity TAS
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005008 hepatocyte growth factor-activated receptor activity TAS
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IBA
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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