4255


Homo sapiens (NCBI)

Features
Gene ID: 4255
  
Biological name :
  
Synonyms : MGMT / O-6-methylguanine-DNA methyltransferase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204880_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034568321
RefSeq - 197304670
RefSeq - 530394832
RefSeq - NC_000010.11
RefSeq - NG_052673.1
RefSeq - NP_002403.2
RefSeq - XP_005252739.1
RefSeq - XP_016871764.1
RefSeq - NM_002412.4
RefSeq - XM_017016275.1
RefSeq - XM_005252682.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000170430 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006266 DNA ligation TAS
 biological_processGO:0006306 DNA methylation IEA
 biological_processGO:0006307 DNA dealkylation involved in DNA repair TAS
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0051593 response to folic acid IEA
 biological_processGO:0060644 mammary gland epithelial cell differentiation IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0071479 cellular response to ionizing radiation IEA
 biological_processGO:2000781 positive regulation of double-strand break repair IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008168 methyltransferase activity TAS
 molecular_functionGO:0009008 DNA-methyltransferase activity TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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