4282


Homo sapiens (NCBI)

Features
Gene ID: 4282
  
Biological name :
  
Synonyms : GIF|GLIF|MMIF / macrophage migration inhibitory factor / MIF
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 217871_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4505185
RefSeq - NC_000022.11
RefSeq - NG_012099.1
RefSeq - NP_002406.1
RefSeq - NT_187633.1
RefSeq - NM_002415.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000240972 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process IDA
 biological_processGO:0002906 negative regulation of mature B cell apoptotic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IDA
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0010739 positive regulation of protein kinase A signaling IDA
 biological_processGO:0010760 negative regulation of macrophage chemotaxis IDA
 biological_processGO:0019752 carboxylic acid metabolic process IDA
 biological_processGO:0030330 DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0030890 positive regulation of B cell proliferation IDA
 biological_processGO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032269 negative regulation of cellular protein metabolic process IEA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IDA
 biological_processGO:0033033 negative regulation of myeloid cell apoptotic process IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0035722 interleukin-12-mediated signaling pathway TAS
 biological_processGO:0042327 positive regulation of phosphorylation IDA
 biological_processGO:0043030 regulation of macrophage activation NAS
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IDA
 biological_processGO:0050715 positive regulation of cytokine secretion IDA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0061078 positive regulation of prostaglandin secretion involved in immune response IEA
 biological_processGO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response IEA
 biological_processGO:0070207 protein homotrimerization IPI
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IGI
 biological_processGO:0071157 negative regulation of cell cycle arrest IDA
 biological_processGO:0090238 positive regulation of arachidonic acid secretion IEA
 biological_processGO:0090344 negative regulation of cell aging IDA
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IDA
 biological_processGO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0031982 vesicle HDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0004167 dopachrome isomerase activity IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005126 cytokine receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0050178 phenylpyruvate tautomerase activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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