4294


Homo sapiens (NCBI)

Features
Gene ID: 4294
  
Biological name :
  
Synonyms : MAP3K10 / MEKK10|MLK2|MST / mitogen-activated protein kinase kinase kinase 10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206362_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - NC_000019.10
RefSeq - XP_006723286.1
RefSeq - XP_011525283.1
RefSeq - XP_011525284.1
RefSeq - XP_024307287.1
RefSeq - 1370475172
RefSeq - 21735550
RefSeq - NP_002437.2
RefSeq - 578834495
RefSeq - 768009305
RefSeq - 768009307
RefSeq - XR_001753691.1
RefSeq - NM_002446.3
RefSeq - XM_006723223.3
RefSeq - XM_011526981.2
RefSeq - XM_011526982.3
RefSeq - XM_024451519.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000130758 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IBA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007224 smoothened signaling pathway IMP
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0007256 activation of JNKK activity IEA
 biological_processGO:0007257 activation of JUN kinase activity ISS
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0043065 positive regulation of apoptotic process IBA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0043507 positive regulation of JUN kinase activity IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0046777 protein autophosphorylation ISS
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0003714 transcription corepressor activity ISS
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0004706 JUN kinase kinase kinase activity ISS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0043425 bHLH transcription factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr