4321


Homo sapiens (NCBI)

Features
Gene ID: 4321
  
Biological name :
  
Synonyms : HME|ME|MME|MMP-12 / matrix metallopeptidase 12 / MMP12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 204580_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 73858572
RefSeq - NC_000011.10
RefSeq - NG_032936.1
RefSeq - NP_002417.2
RefSeq - NM_002426.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000262406 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006508 proteolysis IMP
 biological_processGO:0006606 protein import into nucleus IMP
 biological_processGO:0022617 extracellular matrix disassembly TAS
 biological_processGO:0030574 collagen catabolic process TAS
 biological_processGO:0035313 wound healing, spreading of epidermal cells IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0050691 regulation of defense response to virus by host IEA
 biological_processGO:0060054 positive regulation of epithelial cell proliferation involved in wound healing IDA
 biological_processGO:0060339 negative regulation of type I interferon-mediated signaling pathway IEA
 biological_processGO:0060340 positive regulation of type I interferon-mediated signaling pathway IEA
 biological_processGO:0098586 cellular response to virus IEA
 biological_processGO:1902741 positive regulation of interferon-alpha secretion IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IMP
 cellular_componentGO:0005634 nucleus IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0001047 core promoter binding IMP
 molecular_functionGO:0004175 endopeptidase activity TAS
 molecular_functionGO:0004222 metalloendopeptidase activity TAS
 molecular_functionGO:0004252 serine-type endopeptidase activity TAS
 molecular_functionGO:0005509 calcium ion binding IMP
 molecular_functionGO:0005518 collagen binding IPI
 molecular_functionGO:0008270 zinc ion binding IMP
 molecular_functionGO:0043565 sequence-specific DNA binding IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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