4436


Homo sapiens (NCBI)

Features
Gene ID: 4436
  
Biological name :
  
Synonyms : COCA1|FCC1|HNPCC|HNPCC1|LCFS2|hMSH2 / MSH2 / mutS homolog 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209421_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 384871702
RefSeq - 4557761
RefSeq - 767914585
RefSeq - 767914587
RefSeq - NC_000002.12
RefSeq - NG_007110.2
RefSeq - NP_000242.1
RefSeq - NP_001245210.1
RefSeq - XP_005264389.2
RefSeq - XP_011531169.1
RefSeq - XM_005264332.4
RefSeq - XM_011532867.2
RefSeq - NM_000251.2
RefSeq - NM_001258281.1
RefSeq - XR_001738747.2
RefSeq - XR_939685.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000095002 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000710 meiotic mismatch repair IBA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006119 oxidative phosphorylation IEA
 biological_processGO:0006281 DNA repair IDA
 biological_processGO:0006290 pyrimidine dimer repair IBA
 biological_processGO:0006298 mismatch repair TAS
 biological_processGO:0006301 postreplication repair IDA
 biological_processGO:0006302 double-strand break repair IBA
 biological_processGO:0006311 meiotic gene conversion IBA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007283 spermatogenesis IBA
 biological_processGO:0008340 determination of adult lifespan IEA
 biological_processGO:0008584 male gonad development ISS
 biological_processGO:0010165 response to X-ray ISS
 biological_processGO:0010224 response to UV-B ISS
 biological_processGO:0016446 somatic hypermutation of immunoglobulin genes IBA
 biological_processGO:0016447 somatic recombination of immunoglobulin gene segments ISS
 biological_processGO:0019724 B cell mediated immunity ISS
 biological_processGO:0030183 B cell differentiation ISS
 biological_processGO:0031573 intra-S DNA damage checkpoint IBA
 biological_processGO:0036297 interstrand cross-link repair IBA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IBA
 biological_processGO:0043111 replication fork arrest IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 biological_processGO:0043570 maintenance of DNA repeat elements IMP
 biological_processGO:0045128 negative regulation of reciprocal meiotic recombination IBA
 biological_processGO:0045190 isotype switching ISS
 biological_processGO:0045910 negative regulation of DNA recombination ISS
 biological_processGO:0048298 positive regulation of isotype switching to IgA isotypes IEA
 biological_processGO:0048304 positive regulation of isotype switching to IgG isotypes IEA
 biological_processGO:0051096 positive regulation of helicase activity IDA
 cellular_componentGO:0000228 nuclear chromosome IBA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region HDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032300 mismatch repair complex IBA
 cellular_componentGO:0032301 MutSalpha complex IDA
 cellular_componentGO:0032302 MutSbeta complex IDA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0000400 four-way junction DNA binding IDA
 molecular_functionGO:0000403 Y-form DNA binding IBA
 molecular_functionGO:0000404 heteroduplex DNA loop binding IBA
 molecular_functionGO:0000406 double-strand/single-strand DNA junction binding IBA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003697 single-stranded DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0008094 DNA-dependent ATPase activity IBA
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0019237 centromeric DNA binding IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030983 mismatched DNA binding IDA
 molecular_functionGO:0032137 guanine/thymine mispair binding IMP
 molecular_functionGO:0032138 single base insertion or deletion binding IBA
 molecular_functionGO:0032139 dinucleotide insertion or deletion binding IDA
 molecular_functionGO:0032142 single guanine insertion binding IDA
 molecular_functionGO:0032143 single thymine insertion binding IDA
 molecular_functionGO:0032181 dinucleotide repeat insertion binding IDA
 molecular_functionGO:0032357 oxidized purine DNA binding IDA
 molecular_functionGO:0032405 MutLalpha complex binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043531 ADP binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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